US 12,350,301 B2
Composition comprising three Lactobacillus sp. strains, and use thereof
Bo Gie Yang, Seoul (KR); Myung Ho Jang, Seoul (KR); and Han Sung Lee, Seongnam-si (KR)
Assigned to GI BIOME INC., Seongnam-si (KR)
Appl. No. 18/270,925
Filed by GI BIOME INC., Seongnam-si (KR)
PCT Filed Jun. 30, 2022, PCT No. PCT/KR2022/009479
§ 371(c)(1), (2) Date Jul. 5, 2023,
PCT Pub. No. WO2023/277638, PCT Pub. Date Jan. 5, 2023.
Claims priority of application No. 10-2021-0086148 (KR), filed on Jun. 30, 2021; and application No. 10-2022-0080568 (KR), filed on Jun. 30, 2022.
Prior Publication US 2024/0050495 A1, Feb. 15, 2024
Int. Cl. A61K 35/747 (2015.01); A61P 3/04 (2006.01); A61P 21/00 (2006.01); A61P 39/06 (2006.01); C12N 1/20 (2006.01); C12R 1/25 (2006.01)
CPC A61K 35/747 (2013.01) [A61P 3/04 (2018.01); A61P 21/00 (2018.01); A61P 39/06 (2018.01); C12N 1/205 (2021.05); C12R 2001/25 (2021.05)] 14 Claims
 
1. A composition comprising:
a Lactobacillus fermentum GB102 strain deposited with Korean Collection for Type Cultures (KCTC) with accession number KCTC 14105BP;
a Lactobacillus fermentum GB103 strain deposited with KCTC with accession number KCTC 14106BP;
a Lactobacillus fermentum GB104 strain deposited with KCTC with accession number KCTC 14107BP;
a Bifidobacterium animalis strain;
a Lactobacillus acidophilus strain; and
auxiliary ingredients;
wherein the auxiliary ingredients comprise Andong yam, adlay, Ganoderma lucidum, inulin, red ginseng, and vitamin B2;
wherein a total amount of the Lactobacillus fermentum GB102 strain, the Lactobacillus fermentum GB103 strain, the Lactobacillus fermentum GB104 strain, the Bifidobacterium animalis strain, and the Lactobacillus acidophilus strain is 108 CFU/g to 1013 CFU/g, and
wherein a total amount of the auxiliary ingredients is 70.20 mg.