US 12,350,087 B2
Systems and methods for measuring bone mass density using energy discriminating photon-counting X-ray detector
Glenn Bindley, Victoria (CA); and Krzysztof Iniewski, Port Moody (CA)
Assigned to REDLEN TECHNOLOGIES, INC., Saanichton (CA)
Filed by REDLEN TECHNOLOGIES, INC., Saanichton (CA)
Filed on Mar. 2, 2023, as Appl. No. 18/177,460.
Claims priority of provisional application 63/269,407, filed on Mar. 16, 2022.
Prior Publication US 2023/0293131 A1, Sep. 21, 2023
Int. Cl. A61B 6/50 (2024.01); A61B 6/00 (2024.01); A61B 6/42 (2024.01); G06V 10/762 (2022.01)
CPC A61B 6/505 (2013.01) [A61B 6/4241 (2013.01); A61B 6/5205 (2013.01); G06V 10/762 (2022.01)] 18 Claims
OG exemplary drawing
 
1. A method for determining bone mass density (BMD) of a patient, comprising:
obtaining three-dimensional X-ray scan data of a region of interest (ROI) of the patient using an energy discriminating photon counting radiation detector;
calculating the bone mass density (BMD) of the region of interest of the patient based on detected X-ray photon counts within three or more energy bins;
dividing the three-dimensional scan data into a plurality of voxels;
assigning values corresponding to water, bone, fat and protein composition to each voxel of the plurality of voxels;
generating a three-dimensional image map based on the assigned values corresponding to water, bone, fat and protein composition of each voxel of the plurality of voxels;
comparing the generated three-dimensional image map to the three-dimensional X-ray scan data; and
determining the bone density, fat content and protein content of the ROI of the patient in response to a determination that a difference between the three-dimensional image map and the three-dimensional X-ray scan data is below a threshold error value.