US 12,350,045 B2
Working electrode of a continuous biological sensor
Robert James Boock, Carlsbad, CA (US); and Huashi Zhang, San Juan Capistrano, CA (US)
Assigned to Allez Health Inc., Carlsbad, CA (US)
Filed by Allez Health Inc., Carlsbad, CA (US)
Filed on May 13, 2021, as Appl. No. 17/302,835.
Application 17/302,835 is a division of application No. 16/375,880, filed on Apr. 5, 2019, granted, now 11,013,438.
Claims priority of provisional application 62/796,842, filed on Jan. 25, 2019.
Claims priority of provisional application 62/796,832, filed on Jan. 25, 2019.
Claims priority of provisional application 62/653,821, filed on Apr. 6, 2018.
Prior Publication US 2021/0259598 A1, Aug. 26, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 5/1486 (2006.01); A61B 5/145 (2006.01); C12N 9/04 (2006.01); C12Q 1/00 (2006.01); C25D 7/06 (2006.01); C25D 9/02 (2006.01); G01N 27/327 (2006.01); H01M 4/02 (2006.01); H01M 4/04 (2006.01); H01M 4/1395 (2010.01); H01M 4/1399 (2010.01); H01M 4/96 (2006.01)
CPC A61B 5/14865 (2013.01) [A61B 5/14532 (2013.01); C12N 9/0006 (2013.01); C12Q 1/002 (2013.01); C12Q 1/006 (2013.01); C25D 7/0607 (2013.01); C25D 9/02 (2013.01); G01N 27/3271 (2013.01); G01N 27/3275 (2013.01); H01M 4/02 (2013.01); H01M 4/0402 (2013.01); H01M 4/0419 (2013.01); H01M 4/045 (2013.01); H01M 4/1395 (2013.01); H01M 4/1399 (2013.01); H01M 4/96 (2013.01); A61B 2562/125 (2013.01); C12Y 101/01027 (2013.01); C12Y 101/0103 (2013.01); C12Y 101/03004 (2013.01); H01M 2004/024 (2013.01)] 11 Claims
OG exemplary drawing
 
1. A working electrode for a subcutaneous glucose sensor for use with a continuous glucose monitor for a patient, comprising:
a conductive substrate; and
an enzyme layer on the conductive substrate, the enzyme layer comprising:
glucose oxidase (GOx) enzyme;
a hydrophobic material cross-linked with a self cross-linking acrylic polyol; and
wherein the GOx enzyme is fully entrapped within the hydrophobic material cross-linked with the self cross-linking acrylic polyol.