US 12,350,039 B2
Blood analysis system
Bal Chander, Himachal Pradesh (IN)
Assigned to Bal Chander, Himachal Pradesh (IN)
Appl. No. 17/609,281
Filed by Bal Chander, Himachal Pradesh (IN)
PCT Filed May 8, 2020, PCT No. PCT/IN2020/050415
§ 371(c)(1), (2) Date Nov. 5, 2021,
PCT Pub. No. WO2020/230153, PCT Pub. Date Nov. 19, 2020.
Claims priority of application No. 201911018848 (IN), filed on May 10, 2019.
Prior Publication US 2022/0225903 A1, Jul. 21, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61B 5/145 (2006.01); A61B 5/1455 (2006.01); A61M 1/34 (2006.01); A61M 1/36 (2006.01)
CPC A61B 5/14525 (2013.01) [A61B 5/14546 (2013.01); A61B 5/14557 (2013.01); A61M 1/3618 (2014.02); A61M 1/362 (2014.02); A61M 1/3633 (2013.01); A61M 1/3693 (2013.01); A61M 1/3472 (2013.01); A61M 1/3479 (2014.02); A61M 1/3482 (2014.02); A61M 1/3496 (2013.01); A61M 2205/7554 (2013.01); A61M 2230/20 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A blood analysis system for analysis and correction of blood of a subject, the blood analysis system comprising:
a centrifugation unit to receive blood of a subject, the centrifugation unit is to:
hold capturing molecules, wherein one capturing molecule binds with, to chemically capture, one type of molecule or ion to render the bound molecule or the bound ion unfunctional; and
centrifuge to suspend cellular components with a minimal plasma along with the capturing molecules;
a holding unit coupled to the centrifugation unit to receive plasma with the capturing molecules but without the cellular components from the centrifugation unit and hold the received plasma;
an ion separation unit coupled to the holding unit to receive the plasma from the holding unit, the ion separation unit is to separate anions and cations from the received plasma based on electrostatically-charged semi permeable membranes; and
one or more filtration units to receive ion-free plasma with the capturing molecules expelled from the ion separation unit to filter out one or more specific types of molecules, not bound with the capturing molecules, from the ion-free plasma for detection and correction, before moving the ion-free plasma having the corrected filtered molecules towards a collecting channel for infusing back to the subject,
wherein the ion separation unit is coupled to the holding unit through a channel to receive the received plasma, and the ion separation unit comprises an anion separation unit and a cation separation unit, and
wherein the anion separation unit comprises:
a first cell coupled to the channel and having a first semi-permeable membrane of a specific molecular weight cut-off that allows the anions to pass through; and
a second cell coupled to the channel and having a second SPM, the second SPM being the same as the first SPM,
wherein one of the first cell and the second cell is operated to separate the anions and the other of the first cell and the second cell is operated for declogging,
wherein each of the first cell and the second cell is coupled to a respective concentration unit and a respective detection unit to concentrate and detect, respectively, the filtered anions, and
wherein the detection unit is coupled to a correction unit to correct a concentration of reconstituted anions expelled from the detection unit before passing the corrected anions towards the collecting channel.