US 11,053,525 B2
Microorganisms for producing putrescine or ornithine and process for producing putrescine or ornithine using them
Hee Kyoung Jung, Seoul (KR); Hye Won Um, Gyeonggi-do (KR); Hong Xian Li, Gyeonggi-do (KR); Su Jin Park, Seoul (KR); Young Lyeol Yang, Seoul (KR); Kyoung Min Lee, Gyeonggi-do (KR); and Hyo Hyoung Lee, Incheon (KR)
Assigned to CJ CHEILJEDANG CORPORATION, Seoul (KR)
Appl. No. 15/739,699
Filed by CJ Cheiljedang Corporation, Seoul (KR)
PCT Filed Mar. 29, 2016, PCT No. PCT/KR2016/003198
§ 371(c)(1), (2) Date Dec. 22, 2017,
PCT Pub. No. WO2016/208854, PCT Pub. Date Dec. 29, 2016.
Claims priority of application No. 10-2015-0090021 (KR), filed on Jun. 24, 2015.
Prior Publication US 2018/0187222 A1, Jul. 5, 2018
Int. Cl. C12N 1/20 (2006.01); C12P 13/00 (2006.01); C12P 13/10 (2006.01); C12N 9/10 (2006.01); C12N 9/88 (2006.01)
CPC C12P 13/10 (2013.01) [C12N 1/20 (2013.01); C12N 9/1018 (2013.01); C12N 9/1025 (2013.01); C12N 9/88 (2013.01); C12P 13/001 (2013.01); C12Y 201/03003 (2013.01); C12Y 203/03001 (2013.01); C12Y 401/01017 (2013.01)] 32 Claims
 
1. A modified microorganism of the genus Corynebacterium producing putrescine, wherein an activity of transcriptional regulator of sugar metabolism (SugR) is weakened compared to its endogenous activity and an activity of citrate synthase (GltA) which is inhibited by NADH is enhanced compared to its endogenous activity.