US 11,052,484 B2
System for processing a dried fluid sample substrate and method therefor
Claudio Cherubini, Cham (CH); Andreas Drechsler, Baar (CH); Reto Huesser, Cham (CH); and Emad Sarofim, Hagendorn (CH)
Assigned to Roche Molecular Systems, Inc., Pleasanton, CA (US)
Filed by Roche Molecular Systems, Inc., Pleasanton, CA (US)
Filed on May 17, 2018, as Appl. No. 15/982,317.
Claims priority of application No. 17000846 (EP), filed on May 17, 2017.
Prior Publication US 2018/0333806 A1, Nov. 22, 2018
Int. Cl. B23K 26/16 (2006.01); B23K 26/12 (2014.01); B23K 37/04 (2006.01); G01N 1/04 (2006.01); B23K 26/08 (2014.01); B23K 26/38 (2014.01); G01N 1/28 (2006.01); B23K 26/70 (2014.01); B23K 103/00 (2006.01)
CPC B23K 26/16 (2013.01) [B23K 26/0853 (2013.01); B23K 26/0876 (2013.01); B23K 26/127 (2013.01); B23K 26/38 (2013.01); B23K 26/702 (2015.10); B23K 37/0408 (2013.01); B23K 37/0443 (2013.01); G01N 1/04 (2013.01); G01N 1/286 (2013.01); B23K 2103/32 (2018.08); G01N 2001/2886 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A system (1; 1′) for processing at least one substrate (2) containing a dried fluid sample (21), the system (1; 1′) comprising:
a support configured to position the substrate (2);
a laser device (3) for directing a laser beam (31) to the substrate (2), configured to cut at least one area of the substrate (2) containing the dried fluid sample (21) by means of the laser beam (31);
a container holder (4; 4′) configured to hold and position a container (5) for receiving the cut area, the container holder (4; 4′) being arranged below the substrate (2); and
an extraction subsystem (6) for extracting fume or dust, or both fume and dust, generated when laser cutting the substrate (2), and
wherein the extraction subsystem (6) consists of at least two extraction components (61, 62) sandwiching the substrate (2) there between, wherein the at least two extract components (61, 62) comprises an upper extraction component (61) and a lower extraction component (62), both sandwiching the substrate (2) there between in such a way that the substrate (2) is positioned in between the at least two extraction components (61, 62), wherein the upper extraction component (61) is positioned above the substrate (2), and wherein the lower extraction component (62) is positioned below the substrate.