US 11,052,230 B2
Implantable encapsulation devices
Edward H. Cully, Flagstaff, AZ (US); Edward Gunzel, Oxford, PA (US); Keith Knisley, Flagstaff, AZ (US); Greg Rusch, Newark, DE (US); and Lauren Zambotti, Wilmington, DE (US)
Assigned to W. L. Gore & Associates, Inc., Newark, DE (US)
Filed by W. L. Gore & Associates, Inc., Newark, DE (US)
Filed on Nov. 7, 2017, as Appl. No. 15/806,054.
Claims priority of provisional application 62/419,204, filed on Nov. 8, 2016.
Prior Publication US 2018/0126134 A1, May 10, 2018
Int. Cl. A61M 31/00 (2006.01); A61F 2/02 (2006.01); A61K 9/00 (2006.01); A61L 31/04 (2006.01); A61L 31/14 (2006.01); A61L 31/16 (2006.01); A61M 39/02 (2006.01); A61F 2/30 (2006.01); A61M 39/04 (2006.01)
CPC A61M 31/002 (2013.01) [A61F 2/022 (2013.01); A61K 9/0092 (2013.01); A61L 31/048 (2013.01); A61L 31/14 (2013.01); A61L 31/146 (2013.01); A61L 31/148 (2013.01); A61L 31/16 (2013.01); A61M 39/0247 (2013.01); A61F 2002/30235 (2013.01); A61L 2400/16 (2013.01); A61M 39/04 (2013.01); A61M 2039/0264 (2013.01); A61M 2039/0282 (2013.01)] 47 Claims
OG exemplary drawing
 
1. An implantable encapsulation device comprising:
a plurality of containment tubes interconnected by connection members, each said containment tube having a first access port at a first end thereof and a second access port at a second end thereof, and
a removable manifold fluidly connected to said containment tubes at said first end,
wherein said containment tubes are substantially parallel to each other along a length of said device,
wherein said containment tubes comprise a porous composite material including:
an outer porous polymeric layer that permits ingrowth of vascular tissue; and
an inner polymeric layer disposed adjacent to said outer porous polymeric layer, said inner polymeric layer being impervious to cellular or vascular ingrowth,
wherein said connection members are periodically spaced along a length of said containment tubes a distance from each other, and
wherein said plurality of containment tubes are fluidly interconnected by said connection members.