US 11,051,934 B2
Prosthetic mitral valve with improved anchors and seal
Alexander H. Cooper, Costa Mesa, CA (US); Juliet Laura Schwartz, Yorba Linda, CA (US); Wendy Vo Pham, Garden Grove, CA (US); Hieu Minh Luong, Westminster, CA (US); Julio Cesar Sanchez, Garden Grove, CA (US); Matthew A. Peterson, Costa Mesa, CA (US); J. Brent Ratz, Winchester, MA (US); and Lisong Ai, Irvine, CA (US)
Assigned to Edwards Lifesciences Corporation, Irvine, CA (US)
Filed by Edwards Lifesciences Corporation, Irvine, CA (US)
Filed on Feb. 26, 2019, as Appl. No. 16/286,436.
Claims priority of provisional application 62/781,817, filed on Dec. 19, 2018.
Claims priority of provisional application 62/636,672, filed on Feb. 28, 2018.
Prior Publication US 2019/0262129 A1, Aug. 29, 2019
Int. Cl. A61F 2/24 (2006.01); A61F 2/95 (2013.01)
CPC A61F 2/2409 (2013.01) [A61F 2/2418 (2013.01); A61F 2/2427 (2013.01); A61F 2002/9505 (2013.01); A61F 2220/0008 (2013.01); A61F 2220/0025 (2013.01); A61F 2230/001 (2013.01); A61F 2230/0093 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A mitral valve prosthesis configured to transition between a compressed configuration and an expanded configuration, the prosthesis having a proximal end and a distal end, the prosthesis comprising:
an inner frame comprising:
a body comprising:
a plurality of circumferentially extendable struts with respect to a longitudinal axis of the inner frame; and
a plurality of longitudinally extending struts with respect to the longitudinal axis of the inner frame;
wherein the plurality of circumferentially extendable struts and the plurality of longitudinally extending struts form two or more rows of cells; and
a plurality of inner frame anchoring features extending distally from the body;
wherein the body of the inner frame tapers radially inward from a first larger diameter at a proximal end of the body to a narrowest diameter of an intermediate region of the body and then tapers radially outward from the narrowest diameter of the intermediate region of the body to a second larger diameter at a distal end of the body so as to form a curved hourglass shape when the prosthesis is in the expanded configuration;
an outer frame connected to the inner frame,
wherein a longitudinal length of the outer frame overlaps with at least the intermediate region of the body of the inner frame when the prosthesis is in the expanded configuration;
a valve body connected to a curved interior surface of the inner frame formed by the curved hourglass shape of the body of the inner frame, the valve body comprising a plurality of leaflets arranged to allow blood flow in a first direction and prevent blood flow in a second direction opposite the first direction, wherein the leaflets are adapted to have a longitudinal curvature when the valve body is in an open configuration that follows the curved hourglass shape of the body of the inner frame and conforms to and lies flush against the curved interior surface of the inner frame when the prosthesis is in the expanded configuration, thereby reducing a formation of thrombi between the plurality of leaflets and the curved interior surface of the inner frame; and
a fabric skirt connected to an inner surface of the outer frame and extending distally beyond a distal end of the outer frame, wherein the fabric skirt is adapted for contacting a mitral valve annulus and forming a seal between the prosthesis and the mitral valve annulus.