| CPC G06T 11/008 (2013.01) [A61B 6/5235 (2013.01); A61B 6/5264 (2013.01); G06T 7/344 (2017.01); G06T 2207/10081 (2013.01); G06T 2207/10104 (2013.01); G06T 2207/10108 (2013.01); G06T 2207/20084 (2013.01)] | 20 Claims |

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1. A computer-implemented method for automatic artifact evaluation and correction in medical imaging data, comprising:
obtaining, via a processor, emission-tomography functional image data and a corresponding reconstructed anatomical image volume of a subject, the emission-tomography functional image data and the corresponding reconstructed anatomical image volume comprising at least one organ having natural motion;
pre-determining, via the processor, a dedicated model for spatial mismatch correction of the at least one organ having natural motion;
performing, via the processor, initial image reconstruction of the emission-tomography functional image data to generate a reconstructed emission-tomography functional image volume utilizing attenuation correction based on the corresponding reconstructed anatomical image volume;
identifying, via the processor, relevant anatomical regions, within the reconstructed emission-tomography functional image volume and the corresponding reconstructed anatomical image volume, where functional image quality may be affected by the natural motion of the at least one organ;
identifying and evaluating, via the processor, potential attenuation-correction image artifacts in the reconstructed emission-tomography functional image volume that are related to functional-anatomical spatial mismatch;
estimating, via the processor, model parameters based on confirmed attenuation-correction image artifacts, wherein the model parameters represent the functional-anatomical spatial mismatch;
correcting, via the processor, the corresponding reconstructed anatomical image volume utilizing both the dedicated model and the model parameters to generate a corrected anatomical image volume; and
reconstructing, via the processor, the emission-tomography functional image data utilizing attenuation correction based on the corrected anatomical image volume to generate a corrected emission-tomography functional image volume.
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