US 12,346,998 B2
Artificial intelligence (AI)-based standardized uptake value (SUV) correction and variation assessment for positron emission tomography (PET)
Andreas Georg Goedicke, Aachen (DE); Bin Zhang, Cleveland, OH (US); Andriy Andreyev, Willoughby Hills, OH (US); Andre Frank Salomon, Aachen (DE); Yanfei Mao, Highland Heights, OH (US); Chuanyong Bai, Solon, OH (US); and Zhiqiang Hu, Twinsburg, OH (US)
Assigned to KONINKLIJKE PHILIPS N.V., Eindhoven (NL)
Appl. No. 17/292,044
Filed by KONINKLIJKE PHILIPS N.V., Eindhoven (NL)
PCT Filed Nov. 8, 2019, PCT No. PCT/EP2019/080628
§ 371(c)(1), (2) Date May 7, 2021,
PCT Pub. No. WO2020/099250, PCT Pub. Date May 22, 2020.
Claims priority of provisional application 62/760,124, filed on Nov. 13, 2018.
Prior Publication US 2021/0398329 A1, Dec. 23, 2021
Int. Cl. G06T 11/00 (2006.01); G06N 3/08 (2023.01); G06N 7/04 (2006.01); G06T 7/00 (2017.01)
CPC G06T 11/008 (2013.01) [G06N 3/08 (2013.01); G06N 7/046 (2013.01); G06T 7/0012 (2013.01); G06T 11/005 (2013.01); G06T 2207/10104 (2013.01); G06T 2207/20084 (2013.01); G06T 2207/30096 (2013.01); G06T 2211/40 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A non-transitory computer-readable medium storing instructions readable and executable by at least one electronic processor to perform an imaging method, the method comprising:
reconstructing emission imaging data to generate an emission image of a lesion;
converting intensity values of voxels of the emission image to standardized uptake values (SUV values) for the lesion, the SUV values being computed as a function of a body mass or weight of the patient, a wait time between administration of the radiopharmaceutical and the PET imaging data acquisition, and one or more of a radiopharmaceutical dose and/or a half-life of the radiopharmaceutical;
processing input data using a regression neural network to output an SUV correction factor for the lesion, wherein the input data includes at least two of (i) image data comprising the emission image or a feature vector representing the emission image, (ii) the at least one SUV value, (iii) a size of the lesion, and (iv) reconstruction parameters used in the reconstructing; and
controlling a display device to display at least one of (I) the SUV correction factor and (II) a corrected SUV value generated by applying the SUV correction factor to the at least one SUV value.