US 12,345,792 B2
Apparatus and method for representing organized tissue and constructing configurable phantoms of same
Fergal Kerins, Toronto (CA); and Murugathas Yuwaraj, Markham (CA)
Assigned to Preoperative Performance Inc., Toronto (CA)
Appl. No. 18/032,127
Filed by Preoperative Performance Inc., Toronto (CA)
PCT Filed Oct. 18, 2021, PCT No. PCT/CA2021/051462
§ 371(c)(1), (2) Date Apr. 14, 2023,
PCT Pub. No. WO2022/077125, PCT Pub. Date Apr. 21, 2022.
Claims priority of provisional application 63/093,283, filed on Oct. 18, 2020.
Prior Publication US 2024/0019516 A1, Jan. 18, 2024
Int. Cl. G01R 33/58 (2006.01); G01R 33/563 (2006.01)
CPC G01R 33/58 (2013.01) [G01R 33/56341 (2013.01); G01R 33/56366 (2013.01)] 24 Claims
OG exemplary drawing
 
1. A phantom for use in MR imaging, wherein the phantom comprises:
an outer housing defining an interior volume;
at least one support plate mounted in the interior volume of the outer housing and having a first surface with a plurality of connection locations for selectively receiving a connector of at least one element allowing for configurable phantoms to be created;
the at least one element being (a) at least one isotropic diffusion module, (b) at least one anisotropic diffusion module, (c) at least one perfusion module, or (d) any combination of (a), (b), and (c), the connector of each of the at least one element being releasably matingly connected at one or more of the plurality of connection locations on the first surface of the support plate; and
a matrix material contained within the outer housing, the matrix material being an aqueous fluid,
wherein during MR imaging, the presence of the aqueous fluid, and directionality of fluid molecular diffusion within or through the at least one element are recorded in MR images.