| CPC G01N 21/27 (2013.01) [G01N 21/255 (2013.01); G01N 2021/478 (2013.01)] | 6 Claims |
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1. An optical measurement device comprising:
a measurement unit comprising a light-emitting element configured to emit measurement light to a single detection line of a lateral flow test strip and a light-receiving element configured to receive light obtained from the single detection line by the emission of the measurement light for a predetermined period and to output an output signal in accordance with an intensity of the light; and
a determination unit comprising a computer in communication with the light-receiving element and configured to determine whether or not a sample held in the lateral flow test strip is negative or positive on the basis of a comparison between a measurement value in the single detection line obtained by the measurement unit and a first threshold value set in advance for determining the sample,
wherein the determination unit
determines an initial measurement value based on a first output signal at a first time, and a latter measurement value based on a second output signal at a second time after the first time,
determines whether the measurement value exceeds the first threshold value;
calculates a difference value between an initial measurement value at a first time in the single detection line and a latter measurement value at a second time after the first time in the single detection line when the measurement value in the single detection line exceeds the first threshold value after the sample is held by the lateral flow test strip,
determines whether the difference value exceeds a second threshold value,
determines that the sample is positive when the difference value exceeds a second threshold value set in advance, and
determines that the sample is negative when the difference value is the second threshold value or less.
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4. An optical measurement method comprising:
emitting measurement light from a light-emitting element to a single detection line of a lateral flow test strip and measuring receiving light obtained from the single detection line by the emission of the measurement light for a predetermined period with a light-receiving element configured to output an output signal in accordance with an intensity of the light; and
determining with a computer in communication with the light-receiving element whether or not a sample held by the lateral flow test strip is negative or positive on the basis of a comparison between a measurement value in the single detection line obtained by the measuring and a first threshold value set in advance for determining the sample,
wherein the determining step comprises:
determining an initial measurement value based on a first output signal at a first time, and a latter measurement value based on a second output signal at a second time after the first time,
determining whether the measurement value exceeds the first threshold value;
calculating a difference value between an initial measurement value at a first time in the single detection line and a latter measurement value at a second time after the first time in the single detection line when the measurement value in the single detection line exceeds the first threshold value after the sample is held by the lateral flow test strip,
determining whether the difference value exceeds a second threshold value,
determining that the sample is positive when the difference value exceeds a second threshold value set in advance, and
determining that the sample is negative when the difference value is the second threshold value or less.
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