US 12,345,625 B2
Microscopic object detection device, detection system, and detection method
Takuya Iida, Sakai (JP); Shiho Tokonami, Sakai (JP); Hiroki Ishikawa, Nagaokakyo (JP); Tsutomu Yamasaki, Nagaokakyo (JP); and Hirohito Washida, Nagaokakyo (JP)
Assigned to University Public Corporation Osaka, Osaka (JP); and MURATA MANUFACTURING CO., LTD., Kyoto (JP)
Appl. No. 17/921,420
Filed by University Public Corporation Osaka, Osaka (JP); and Murata Manufacturing Co., Ltd., Nagaokakyo (JP)
PCT Filed May 7, 2021, PCT No. PCT/JP2021/017454
§ 371(c)(1), (2) Date Oct. 26, 2022,
PCT Pub. No. WO2021/225157, PCT Pub. Date Nov. 11, 2021.
Claims priority of application No. 2020-082483 (JP), filed on May 8, 2020.
Prior Publication US 2023/0194413 A1, Jun. 22, 2023
Int. Cl. G01N 21/17 (2006.01); G01N 21/64 (2006.01); G01N 33/58 (2006.01)
CPC G01N 21/171 (2013.01) [G01N 21/6456 (2013.01); G01N 2021/1714 (2013.01); G01N 33/582 (2013.01); G01N 2201/06113 (2013.01)] 12 Claims
OG exemplary drawing
 
1. A detection device comprising:
a light source unit that emits light with which a collecting kit is irradiated;
an optical receiver that detects light from a liquid sample held on the collecting kit and outputs a detection signal of the light, the liquid sample including a plurality of microscopic objects; and
a processor that calculates an amount of the plurality of microscopic objects collected in the liquid sample based on a change of the detection signal over time, the change including (i) a slope of an approximate straight line obtained by regression in a time domain of the detection signal of a predetermined period after start of light irradiation of a photothermal conversion region, or (ii) an intensity ratio of two detection signals acquired along with light irradiation of the photothermal conversion region; wherein
the detection device detects the plurality of microscopic objects in the liquid sample by collecting the plurality of microscopic objects dispersed in the liquid sample with the collecting kit, the collecting kit having the photothermal conversion region that converts light into heat and being configured to hold the liquid sample on the photothermal conversion region.