US 12,344,906 B2
System and method for reducing content of 5-hydroxymethylfurfural in high fructose corn syrup
Shengrong Chen, Zhejiang (CN); Jun Zhuge, Zhejiang (CN); Yuqing Cheng, Zhejiang (CN); Xinfeng Han, Zhejiang (CN); and Jiaxing Luo, Zhejiang (CN)
Assigned to Zhejiang Huakang Pharmaceutical Co., Ltd., Quzhou (CN)
Appl. No. 17/775,002
Filed by Zhejiang Huakang Pharmaceutical Co., Ltd., Zhejiang (CN)
PCT Filed Feb. 7, 2021, PCT No. PCT/CN2021/075695
§ 371(c)(1), (2) Date May 6, 2022,
PCT Pub. No. WO2021/160053, PCT Pub. Date Aug. 19, 2021.
Claims priority of application No. 202010087317.9 (CN), filed on Feb. 11, 2020.
Prior Publication US 2022/0389526 A1, Dec. 8, 2022
Int. Cl. C13K 1/08 (2006.01); B01J 47/028 (2017.01); B01J 47/04 (2006.01)
CPC C13K 1/08 (2013.01) [B01J 47/028 (2013.01); B01J 47/04 (2013.01)] 9 Claims
OG exemplary drawing
 
1. A system for reducing a content of 5-hydroxymethylfurfural in a high fructose syrup, comprising:
an ion exchange positive column and an ion exchange negative column for removing cations and anions from an F42 high fructose syrup;
a heat exchanger unit for reducing the temperature of an F55 high fructose syrup obtained from the F42 high fructose syrup to obtain a heat-exchanged F55 high fructose syrup;
a mixed bed column for purifying the heat-exchanged F55 high fructose syrup to obtain a purified F55 high fructose syrup; and
an evaporation tank for concentrating the purified F55 high fructose syrup,
wherein the heat exchanger unit comprises a first heat exchanger and a second heat exchanger connected in series,
the first heat exchanger comprises a first inlet, a second inlet, a first outlet, and a second outlet,
the second heat exchanger comprises a first inlet, a second inlet, a first outlet, and a second outlet,
the heat exchanger unit is configured to allow the F55 high fructose syrup to enter the first heat exchanger through the first inlet of the first heat exchanger, exit the first outlet of the first heat exchanger, enter the second heat exchanger through the first inlet of the second heat exchanger, exit the first outlet of the second heat exchanger, and enter a liquid inlet of the mixed bed column through a liquid inlet pipe, and
the heat exchanger unit is further configured to allow the F55 high fructose syrup purified by the mixed bed column to enter the second inlet of the first heat exchanger through an outlet of the mixed bed column, exit the second outlet of the first heat exchanger, and enter a liquid inlet of the evaporation tank,
wherein the second inlet of the second heat exchanger is in communication with cooling water through a water inlet pipe, and the second heat exchanger is configured to allow the heat-exchanged cooling water to exit the second outlet of the second heat exchanger.