US 12,344,879 B2
Transgenic bacteria with expanded amino acid usage and nucleic acid molecules for use in the same
Andrew D. Ellington, Austin, TX (US); and Ross Thyer, Austin, TX (US)
Assigned to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US)
Filed by BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US)
Filed on May 26, 2023, as Appl. No. 18/324,843.
Application 18/324,843 is a continuation of application No. 16/786,995, filed on Feb. 10, 2020, granted, now 11,661,618.
Application 16/786,995 is a continuation of application No. 15/380,560, filed on Dec. 15, 2016, granted, now 10,557,160, issued on Jan. 22, 2020.
Claims priority of provisional application 62/267,498, filed on Dec. 15, 2015.
Prior Publication US 2023/0366003 A1, Nov. 16, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. C12P 21/06 (2006.01); C12N 9/00 (2006.01); C12N 9/86 (2006.01); C12N 15/11 (2006.01); C12N 15/67 (2006.01); C12P 21/02 (2006.01)
CPC C12P 21/02 (2013.01) [C12N 9/86 (2013.01); C12N 9/93 (2013.01); C12N 15/11 (2013.01); C12N 15/67 (2013.01); C12Y 305/02006 (2013.01)] 19 Claims
 
1. A recombinant nucleic acid molecule, wherein the molecule encodes a tRNA and is at least 92% identical to SEQ ID NO: 19 or SEQ ID NO: 20; and wherein the tRNA encoded by the recombinant nucleic acid molecule comprises a U at a position corresponding to position 49.