| CPC C12N 15/8217 (2013.01) [C12N 15/8218 (2013.01); C12N 15/825 (2013.01); C12N 15/827 (2013.01); C12N 15/8273 (2013.01); C12N 15/8274 (2013.01); C12N 15/8281 (2013.01); C12N 15/8282 (2013.01); C12N 15/8283 (2013.01); C12N 15/8286 (2013.01)] | 16 Claims |
|
1. One or more vectors or polynucleotides comprising:
(a) a polynucleotide encoding a VGEvy gene switch, comprising:
(i) a transactivation domain;
(ii) a DNA-binding domain; and
(iii) a ligand-binding domain having the amino acid sequence of SEQ ID NO:2;
(b) a nucleic acid encoding a protein or an RNA that inhibits a fungus; and
(c) a regulatory element operably connected 5′ of (b)
wherein the VGEvy gene switch induces expression of (b) in the presence of a chemical ligand.
|