US 12,343,531 B2
Electro-magnetic induction device and method of activating a target tissue
Ronja Müller-Bruhn, Windisch (CH)
Assigned to STIMIT AG, Biel/Bienne (CH)
Appl. No. 16/968,025
Filed by STIMIT AG, Biel/Bienne (CH)
PCT Filed Feb. 6, 2019, PCT No. PCT/EP2019/052876
§ 371(c)(1), (2) Date Aug. 6, 2020,
PCT Pub. No. WO2019/154837, PCT Pub. Date Aug. 15, 2019.
Claims priority of application No. 00135/18 (CH), filed on Feb. 6, 2018; and application No. 00733/18 (CH), filed on Jun. 7, 2018.
Prior Publication US 2021/0361939 A1, Nov. 25, 2021
Int. Cl. A61N 1/36 (2006.01); A61M 16/00 (2006.01); A61M 16/20 (2006.01); A61N 1/04 (2006.01); A61N 1/40 (2006.01); A61N 2/00 (2006.01); A61N 2/02 (2006.01); A61N 7/00 (2006.01)
CPC A61N 1/3601 (2013.01) [A61M 16/0051 (2013.01); A61M 16/024 (2017.08); A61M 16/204 (2014.02); A61M 16/205 (2014.02); A61N 1/0456 (2013.01); A61N 1/36017 (2013.01); A61N 1/40 (2013.01); A61N 2/002 (2013.01); A61N 2/006 (2013.01); A61N 2/02 (2013.01); A61N 7/00 (2013.01); A61M 2016/0027 (2013.01); A61M 2016/0036 (2013.01); A61M 2205/054 (2013.01); A61M 2205/057 (2013.01); A61M 2205/058 (2013.01); A61M 2210/1014 (2013.01); A61N 2007/0026 (2013.01)] 25 Claims
OG exemplary drawing
 
1. An electro-magnetic induction device for activating a diaphragm of a human or animal body when being ventilated by a ventilation machine, the electro-magnetic induction device comprising:
an electro-magnetic field generator with a coil design configured to generate a spatial electro-magnetic field having a targeted shape allowing for specifically stimulating one or both Phrenic nerves of a neural system of the human or animal body while lowering or preventing stimulation of other nerves or tissue neighboring, surrounding, or overlapping a Phrenic nerve of the one or both Phrenic nerves;
a mounting arrangement configured to hold the coil design at a neck of the human or animal body such that one or both Phrenic nerves of the neural system of the human or animal body can be reached by the targeted shape of the electro-magnetic field generated by the coil design of the electro-magnetic field generator;
a sensor member configured to detect an activation of the diaphragm of the human or animal body, wherein the sensor member comprises a flow sensor having an adaptor connectable to a respiratory system of the human or animal body;
an electro-magnetic field adjustment mechanism configured to adjust a position of the electro-magnetic field generated by the coil design;
a calibration unit in communication with the sensor member and with the electro-magnetic field adjustment mechanism, wherein the calibration unit is configured
to control the electro-magnetic field adjustment mechanism to vary the position of the electro-magnetic field generated by the coil design,
to receive an activation feedback signal from the sensor member upon detection of the activation of the diaphragm of the human or animal body, and
to control the electro-magnetic field adjustment mechanism to stop variation of the position of the electro-magnetic field generated by the coil design when the activation feedback signal is received; and
a controller in communication with the flow sensor and configured to regulate the activation of the diaphragm in coordination with a breathing scheme such that activation of the diaphragm via the one or both Phrenic nerves is coordinated with the ventilation of the human or animal body.