US 12,343,530 B2
Device and implantation system for electrical stimulation of biological systems
Virender K. Sharma, Paradise Valley, AZ (US); Edy Sofer, Los Angeles, CA (US); Paul V. Goode, Round Rock, TX (US); Bevil Hogg, Murrieta, CA (US); Shai Policker, Tenafly, NJ (US); Matthew Joseph Gani, Seattle, WA (US); Jay Miazga, Seattle, WA (US); and Kaila Raby, Albuquerque, NM (US)
Filed by Paras Holdings, LLC, Dallas, TX (US)
Filed on Nov. 4, 2022, as Appl. No. 18/052,667.
Application 18/052,667 is a continuation of application No. 16/297,222, filed on Mar. 8, 2019, granted, now 11,517,750.
Application 16/297,222 is a continuation of application No. 15/443,983, filed on Feb. 27, 2017, granted, now 10,272,242, issued on Apr. 30, 2019.
Application 15/443,983 is a continuation of application No. 14/665,226, filed on Mar. 23, 2015, granted, now 9,616,225, issued on Apr. 11, 2017.
Application 14/665,226 is a continuation of application No. 13/463,803, filed on May 3, 2012, granted, now 9,020,597, issued on Apr. 28, 2015.
Application 13/463,803 is a continuation in part of application No. 13/419,255, filed on Mar. 13, 2012, granted, now 8,538,534, issued on Sep. 17, 2013.
Application 13/463,803 is a continuation in part of application No. 13/041,063, filed on Mar. 4, 2011, granted, now 8,712,529, issued on Apr. 29, 2014.
Application 13/419,255 is a continuation of application No. 12/300,614, granted, now 8,160,709, issued on Apr. 17, 2012, previously published as PCT/US2007/068907, filed on May 14, 2007.
Claims priority of provisional application 61/482,145, filed on May 3, 2011.
Claims priority of provisional application 61/444,849, filed on Feb. 21, 2011.
Claims priority of provisional application 61/422,967, filed on Dec. 14, 2010.
Claims priority of provisional application 61/371,146, filed on Aug. 5, 2010.
Claims priority of provisional application 61/328,702, filed on Apr. 28, 2010.
Claims priority of provisional application 61/318,843, filed on Mar. 30, 2010.
Claims priority of provisional application 61/310,755, filed on Mar. 5, 2010.
Claims priority of provisional application 60/801,452, filed on May 18, 2006.
Prior Publication US 2023/0158297 A1, May 25, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61N 1/36 (2006.01); A61B 5/00 (2006.01); A61N 1/05 (2006.01); A61B 5/0538 (2021.01); A61B 5/11 (2006.01)
CPC A61N 1/36007 (2013.01) [A61B 5/4836 (2013.01); A61N 1/0517 (2013.01); A61N 1/36139 (2013.01); A61N 1/3614 (2017.08); A61N 1/36171 (2013.01); A61N 1/36175 (2013.01); A61N 1/36178 (2013.01); A61B 5/0538 (2013.01); A61B 5/1116 (2013.01)] 21 Claims
OG exemplary drawing
 
1. A system for treating a patient with gastroesophageal reflux disease, comprising:
at least one electrode positioned in electrical communication with the patient's lower esophageal sphincter (LES);
a waveform generator operably coupled to said at least one electrode;
a controller configured to electrically stimulate the LES to increase the pressure or function of the LES from a first level to a second level, wherein said increase in LES pressure or function above the first level occurs during stimulation and continues after stimulation ceases and wherein said controller controls the waveform generator to repeatedly:
generate and apply an electrical pulse train to the LES through the at least one electrode for a stimulation period, and
terminate the electrical pulse train for a rest period.