	US 12,343,451 B2
	Methods of preparing personalized blood vessels
Raimund Strehl, Gothenburg (SE)
Assigned to VeriGraft AB, Gothenburg (SE)
Filed by VeriGraft AB, Gothenburg (SE)
Filed on Oct. 17, 2022, as Appl. No. 17/967,250.
Application 17/967,250 is a continuation of application No. 16/529,973, filed on Aug. 2, 2019, granted, now 11,471,567.
Claims priority of provisional application 62/714,200, filed on Aug. 3, 2018.
Prior Publication US 2023/0093436 A1, Mar. 23, 2023
Int. Cl. A61L 27/38 (2006.01); A61L 27/36 (2006.01); A61L 27/50 (2006.01); A61L 27/54 (2006.01); A61L 33/00 (2006.01); C12M 1/00 (2006.01); C12M 1/12 (2006.01); C12M 1/34 (2006.01); C12M 3/00 (2006.01); G01N 33/66 (2006.01)

CPC A61L 27/507 (2013.01) [A61L 27/3687 (2013.01); A61L 27/3804 (2013.01); A61L 27/3882 (2013.01); A61L 27/54 (2013.01); A61L 33/0011 (2013.01); C12M 21/08 (2013.01); C12M 25/14 (2013.01); C12M 29/00 (2013.01); C12M 41/26 (2013.01); C12M 41/30 (2013.01); C12M 41/34 (2013.01); G01N 33/66 (2013.01); A61L 2300/21 (2013.01); A61L 2300/232 (2013.01); A61L 2300/236 (2013.01); A61L 2300/414 (2013.01); A61L 2300/42 (2013.01); A61L 2430/40 (2013.01)]

52 Claims

1. A bioreactor for preparing a personalized blood vessel, the bioreactor comprising a peristaltic pump, a container comprising a sampling port, a first connector, and a second connector, wherein the first and second connectors are directly or indirectly connected to the container, wherein each connector is connected to an end of a tubular scaffold for preparing a personalized blood vessel wherein when the first and second connectors are connected to the two ends of the tubular scaffold, the peristaltic pump mediates the circulation of a suspension or solution in a closed circuit, wherein the bioreactor further comprises one or more sensors for measuring glucose level.