	US 12,343,450 B2
	Biologic filler for restoring and regenerating tissue
Sherry L. Voytik-Harbin, Zionsville, IN (US); and Theodore J. Puls, Carmel, IN (US)
Assigned to GENIPHYS, INC., Zionsville, IN (US)
Filed by GENIPHYS, INC., Zionsville, IN (US)
Filed on Dec. 21, 2021, as Appl. No. 17/558,073.
Application 17/558,073 is a continuation of application No. PCT/US2021/015277, filed on Jan. 27, 2021.
Claims priority of provisional application 63/015,946, filed on Apr. 27, 2020.
Claims priority of provisional application 62/966,398, filed on Jan. 27, 2020.
Prior Publication US 2022/0257836 A1, Aug. 18, 2022
Int. Cl. A61L 27/50 (2006.01); A61L 27/22 (2006.01); A61L 27/24 (2006.01); A61L 27/54 (2006.01)

CPC A61L 27/502 (2013.01) [A61L 27/227 (2013.01); A61L 27/24 (2013.01); A61L 27/54 (2013.01); A61L 2400/06 (2013.01)]

19 Claims

1. A method for filling a tissue void formed by the surgical removal of soft tissue from a patient, the method comprising: introducing into the tissue void a polymerizable collagen composition comprising a solution of oligomeric collagen in an amount to fill the void; and polymerizing the polymerizable collagen composition in situ to form a shape-retaining collagen scaffold having viscoelastic properties similar to soft tissues.