US 12,343,424 B2
Photochemically stable, non-leaching, bridged polysilsesquioxane based sunscreens
Douglas A. Loy, Tucson, AZ (US); and Stephanie H. Tolbert, Tucson, AZ (US)
Assigned to ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA, Tucson, AZ (US)
Filed by ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA, Tucson, AZ (US)
Filed on May 23, 2022, as Appl. No. 17/750,970.
Application 17/750,970 is a continuation in part of application No. 16/074,043, granted, now 11,389,386, previously published as PCT/US2017/015588, filed on Jan. 30, 2017.
Application 17/750,970, with international filing date May 23, 2022 is a continuation in part of application No. 15/980,617, filed on May 15, 2018, abandoned.
Claims priority of provisional application 62/506,972, filed on May 16, 2017.
Claims priority of provisional application 62/288,795, filed on Jan. 29, 2016.
Prior Publication US 2022/0339091 A1, Oct. 27, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 8/898 (2006.01); A61K 8/892 (2006.01); A61Q 17/04 (2006.01)
CPC A61K 8/898 (2013.01) [A61K 8/892 (2013.01); A61Q 17/04 (2013.01); A61K 2800/413 (2013.01); A61K 2800/54 (2013.01); A61K 2800/57 (2013.01); A61K 2800/805 (2013.01)] 20 Claims
 
1. A sunscreen composition comprising one or more monomers of a bridged compound according to Formula I:

OG Complex Work Unit Chemistry
wherein A is a UV absorbing moiety,
wherein L1 is a linker group according to Formula II, III, or IV:

OG Complex Work Unit Chemistry
wherein B is a trialkoxysilyl group,
wherein n is at least 2,
wherein L1 is covalently bonded to A to effectively prevent leeching of A from the sunscreen composition, wherein the multiple trialkoxysilyl groups of the bridged compound monomers are polymerized to form bridged polysilsesquioxane-based sunscreen particles, and wherein the sunscreen composition is resistant to photo-degradation.