US 12,343,423 B2
Dissolvable solid article containing preservatives
Ian-Ling Lim, Singapore (SG); Kai Wei Kelvin Lee, Singapore (SG); Shikhar Gupta, Singapore (SG); Minoru Kobayashi, Singapore (SG); Toshiyuki Okada, Singapore (SG); and Robert Wayne Glenn, Jr., Singapore (SG)
Assigned to The Procter & Gamble Company, Cincinnati, OH (US)
Filed by The Procter & Gamble Company, Cincinnati, OH (US)
Filed on Jan. 20, 2022, as Appl. No. 17/580,180.
Claims priority of provisional application 63/139,800, filed on Jan. 21, 2021.
Prior Publication US 2022/0226227 A1, Jul. 21, 2022
Int. Cl. A61K 8/81 (2006.01); A61K 8/02 (2006.01); A61K 8/34 (2006.01); A61K 8/365 (2006.01); A61K 8/44 (2006.01); A61Q 5/02 (2006.01); A61Q 5/12 (2006.01); A61Q 19/00 (2006.01); A61Q 19/10 (2006.01)
CPC A61K 8/8135 (2013.01) [A61K 8/0208 (2013.01); A61K 8/34 (2013.01); A61K 8/365 (2013.01); A61K 8/44 (2013.01); A61Q 19/00 (2013.01); A61K 2800/10 (2013.01); A61K 2800/524 (2013.01); A61Q 5/02 (2013.01); A61Q 5/12 (2013.01); A61Q 19/007 (2013.01); A61Q 19/10 (2013.01)] 11 Claims
 
1. A dissolvable solid article, comprising by weight of the article;
a. from about 10% to about 30% of a water soluble polymer comprising polyvinyl alcohol;
b. from about 35% to about 65% of a surfactant system comprising sodium lauryl sulfate and sodium laureth sulfate;
c. from about 0.5% to about 1.5% of ethylenediaminetetraacetic acid;
d. from about 0.3% to about 3% of an aromatic carboxylic acid chosen from benzoic acids, salts thereof, or mixtures thereof;
e. from about 0.25% to about 1.5% of a hydroxyacetophenone;
f. from about 0.1% to about 3% of a potassium sorbate; and
g. from about 4% to about 15% of at least one non-aromatic organic alpha hydroxy acids and salts thereof chosen from citric acid, lactic acid, and/or gluconic acid, wherein the solid article is an open cell pore structure;
wherein when the dissolvable article is dissolved with 20 part water to 1 part of the dissolvable article to form a dilution, the dilution comprises a pH of from about 3 to 5;
wherein the test dilution comprises a ≥2 log reduction at day 2, a ≥3 log reduction at Day 7, and a log reduction that is ≥ the log reduction at Day 7 at Day 28 for bacteria according to the MST Bacteria Result and the dilution comprises a ≥2 log reduction at day 14 and a log reduction that is ≥ the log reduction at Day 14 at Day 28 for yeast according to the MST Yeast Result.