	US 12,343,375 B2
	Spray dried formulation of a cholera toxin B subunit variant
Krystal Hamorsky, Owensboro, KY (US); and Nobuyuki Matoba, Owensboro, KY (US)
Assigned to University of Louisville Research Foundation, Inc., Louisville, KY (US)
Filed by University of Louisville Research Foundation, Inc., Louisville, KY (US)
Filed on Feb. 9, 2022, as Appl. No. 17/650,386.
Claims priority of provisional application 63/147,521, filed on Feb. 9, 2021.
Prior Publication US 2022/0249601 A1, Aug. 11, 2022
Int. Cl. A61K 38/00 (2006.01); A61K 9/00 (2006.01); A61K 9/16 (2006.01); A61K 38/16 (2006.01); C07K 14/00 (2006.01); C07K 14/28 (2006.01)

CPC A61K 38/164 (2013.01) [A61K 9/0053 (2013.01); A61K 9/1623 (2013.01); A61K 9/1694 (2013.01)]

20 Claims

1. A powder comprising a cholera toxin B subunit variant and mannitol, wherein the cholera toxin B subunit variant and mannitol have a weight ratio of between about 1:3.6 and about 1:45.5.