US 12,343,340 B2
Methods of using low dose naltrexone to treat chronic pain
Amol N. Soin, Dayton, OH (US); Shweta U. Sinkar, San Diego, CA (US); and Robert P. Giannini, Jr., Riverside, CA (US)
Assigned to Soin Therapeutics LLC, Dayton, OH (US)
Filed by Amol N. Soin, Dayton, OH (US)
Filed on Jun. 13, 2022, as Appl. No. 17/839,453.
Application 17/839,453 is a continuation in part of application No. 17/527,336, filed on Nov. 16, 2021, granted, now 11,752,143.
Claims priority of provisional application 63/132,628, filed on Dec. 31, 2020.
Prior Publication US 2022/0305004 A1, Sep. 29, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/485 (2006.01); A61K 9/20 (2006.01); A61K 9/50 (2006.01); A61P 25/04 (2006.01)
CPC A61K 31/485 (2013.01) [A61K 9/2054 (2013.01); A61K 9/5078 (2013.01); A61K 9/5084 (2013.01); A61P 25/04 (2018.01)] 20 Claims
 
1. A method for treatment of a chronic pain disorder in a patient, the method comprising administering to the patient a first amount of naltrexone in an immediate-release agent and a second amount of naltrexone in a modified-release agent, wherein the first amount of naltrexone and the second amount of naltrexone combined equal a total amount of naltrexone that is approximately 2 mg.