US 12,343,315 B2
Topical cannabinoid compositions for clear skin
Frantz Henri Emmanuel Le Devedec, North York (CA); Akm Abdul Hai, Etobicoke (CA); Aras Azadian, Toronto (CA); Setu Nimish Purohit, Toronto (CA); Justin Michael Grant, Toronto (CA); and Samantha Carolyn Watt, Toronto (CA)
Assigned to Avicanna Inc., Toronto (CA)
Filed by Avicanna Inc., Toronto (CA)
Filed on Oct. 21, 2020, as Appl. No. 17/075,764.
Claims priority of provisional application 62/923,905, filed on Oct. 21, 2019.
Prior Publication US 2021/0113490 A1, Apr. 22, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/05 (2006.01); A61K 8/04 (2006.01); A61K 8/34 (2006.01); A61K 8/9789 (2017.01); A61K 9/06 (2006.01); A61K 31/015 (2006.01); A61K 36/53 (2006.01); A61K 36/61 (2006.01); A61P 17/10 (2006.01); A61Q 19/00 (2006.01)
CPC A61K 31/05 (2013.01) [A61K 8/042 (2013.01); A61K 8/347 (2013.01); A61K 8/9789 (2017.08); A61K 9/06 (2013.01); A61K 31/015 (2013.01); A61K 36/53 (2013.01); A61K 36/61 (2013.01); A61P 17/10 (2018.01); A61Q 19/00 (2013.01)] 10 Claims
 
1. A topical cannabinoid homogenous gel emulsion composition comprising
a cannabinoid at 0.1-10% (w/w),
an antioxidant at 0.01-5% (w/w),
an anti-microbial agent at 0.01-2% (w/w),
an anti-inflammatory agent at 0.01-5% (w/w) and
a skin conditioning agent at 0.01-5% (w/w),
wherein the topical cannabinoid homogenous gel emulsion composition comprises less than 20% (w/w) of simple polyol,
wherein the cannabinoid is cannabidiol (CBD),
wherein the anti-inflammatory agent is beta-caryophyllene, and
wherein the topical cannabinoid homogenous gel emulsion composition further comprises a humectant at 1-10% (w/w),
a thickening agent at 0.01-10% (w/w),
a gel-forming agent at 0.1-5% (w/w),
a preservative at 0.1-3% (w/w),
an emollient at 1-3% (w/w),
a non-ionic surfactant at 1-15% (w/w),
a penetration enhancer at 1-5% (w/w),
a fragrance agent at 0.01-2% (w/w),
a pH adjusting agent in a quantity sufficient for the topical cannabinoid homogenous gel emulsion composition to maintain pH 5-7, and
water to make up 100% by weight,
wherein the gel-forming agent is carbomer,
wherein the emollient is isopropyl myristate, and
wherein the penetration enhancer is diethylene glycol monoethyl ether.