US 12,343,255 B2
Device and method with reduced pacemaker rate in heart valve replacement
Stefan Schreck, San Clemente, CA (US); Hussain S. Rangwala, Villa Park, CA (US); and Payam Saffari, Aliso Viejo, CA (US)
Assigned to JenaValve Technology, Inc., Irvine, CA (US)
Filed by JenaValve Technology, Inc., Irvine, CA (US)
Filed on Apr. 12, 2024, as Appl. No. 18/634,703.
Application 18/634,703 is a continuation of application No. 17/664,414, filed on May 22, 2022.
Application 17/664,414 is a continuation of application No. 16/926,585, filed on Jul. 10, 2020, granted, now 11,337,800, issued on May 24, 2022.
Application 16/926,585 is a continuation of application No. 15/570,897, granted, now 10,709,555, issued on Jul. 14, 2020, previously published as PCT/EP2016/058532, filed on Apr. 18, 2016.
Claims priority of provisional application 62/155,849, filed on May 1, 2015.
Prior Publication US 2024/0261091 A1, Aug. 8, 2024
Int. Cl. A61F 2/24 (2006.01); A61L 31/18 (2006.01)
CPC A61F 2/2418 (2013.01) [A61L 31/18 (2013.01); A61F 2210/0014 (2013.01); A61F 2230/0013 (2013.01); A61F 2230/0054 (2013.01); A61F 2230/0056 (2013.01); A61F 2230/006 (2013.01); A61F 2250/0032 (2013.01); A61F 2250/0097 (2013.01); A61F 2250/0098 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A heart valve prosthesis for implantation at a native valve site, the heart valve prosthesis comprising:
a stent comprising a plurality of interconnected cells, the plurality of interconnected cells comprising a ring of cells disposed at an inflow end of the heart valve prosthesis, the stent configured to transition from a non-expanded state to an expanded state at the native valve site;
a prosthetic valve coupled to an inner surface of the stent;
a plurality of locators extending from the stent for positioning the heart valve prosthesis at the native valve site, each locator of the plurality of locators defined by a single elongated wire extension extending to a tip, the tip being at a free end of the locator, each locator configured to extend with respect to the stent such that at least a portion of a respective native leaflet at the native valve site is sandwiched between such locator and the stent in the expanded state; and
a stent cover coupled to the stent and covering at least a portion of the stent, the stent cover forming part of the prosthetic valve;
wherein the stent cover and the stent are configured to form a seal between the heart valve prosthesis and the native valve site to prevent blood flow between the heart valve prosthesis and the native valve site;
wherein the tip at the free end of each locator is configured to contact a cusp or respective native leaflet, and wherein each locator is configured to deform upon contact with the cusp or respective native leaflet;
wherein a shortest distance from the free end of the plurality of locators to the inflow end of the heart valve prosthesis being less in the expanded state than a shortest distance from the free end of the plurality of locators to the inflow end of the heart valve prosthesis in the non-expanded state.