US 12,342,826 B2
Method of identifying a biologically-active composition from a biofilm
Eva A. Berkes, Sarasota, FL (US); Nicholas T. Monsul, Sarasota, FL (US); and Frederick T. Boehm, Sarasota, FL (US)
Assigned to QUORUM INNOVATIONS, LLC, Sarasota, FL (US)
Filed by QUORUM INNOVATIONS, LLC, Sarasota, FL (US)
Filed on Nov. 19, 2023, as Appl. No. 18/513,577.
Application 18/513,577 is a continuation of application No. 17/457,806, filed on Dec. 6, 2021, granted, now 11,825,848.
Application 17/457,806 is a continuation of application No. 16/699,383, filed on Nov. 29, 2019, granted, now 11,191,277, issued on Dec. 7, 2021.
Application 16/699,383 is a continuation of application No. 16/105,017, filed on Aug. 20, 2018, granted, now 10,925,908, issued on Feb. 23, 2021.
Application 16/105,017 is a continuation of application No. 15/626,971, filed on Jun. 19, 2017, granted, now 10,086,025, issued on Oct. 2, 2018.
Application 15/626,971 is a continuation of application No. 15/484,842, filed on Apr. 11, 2017, granted, now 10,004,771, issued on Jun. 26, 2018.
Application 15/484,842 is a continuation of application No. 15/412,712, filed on Jan. 23, 2017, granted, now 9,919,012, issued on Mar. 20, 2018.
Application 15/412,712 is a continuation of application No. 15/349,420, filed on Nov. 11, 2016, granted, now 9,713,631, issued on Jul. 25, 2017.
Application 15/412,712 is a continuation of application No. 15/349,371, filed on Nov. 11, 2016, granted, now 9,717,765, issued on Aug. 1, 2017.
Application 15/349,420 is a continuation of application No. 13/503,325, granted, now 9,504,739, issued on Nov. 29, 2016, previously published as PCT/US2011/059370, filed on Nov. 4, 2011.
Application 15/349,420 is a continuation of application No. 13/503,325, granted, now 9,504,739, issued on Nov. 29, 2016, previously published as PCT/US2011/059370, filed on Nov. 4, 2011.
Claims priority of provisional application 61/447,735, filed on Mar. 1, 2011.
Prior Publication US 2024/0099308 A1, Mar. 28, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. A01N 63/20 (2020.01); A61K 8/34 (2006.01); A61K 8/67 (2006.01); A61K 8/98 (2006.01); A61K 8/99 (2017.01); A61K 9/00 (2006.01); A61K 35/644 (2015.01); A61K 35/74 (2015.01); A61K 35/744 (2015.01); A61K 35/747 (2015.01); A61K 39/09 (2006.01); A61K 45/06 (2006.01); A61K 47/10 (2017.01); A61Q 11/00 (2006.01); A61Q 17/00 (2006.01); A61Q 19/00 (2006.01); A61Q 19/10 (2006.01); C12N 1/20 (2006.01); C12Q 1/04 (2006.01); C12Q 1/18 (2006.01); A61K 36/61 (2006.01); A61K 39/39 (2006.01)
CPC A01N 63/20 (2020.01) [A61K 8/34 (2013.01); A61K 8/67 (2013.01); A61K 8/981 (2013.01); A61K 8/988 (2013.01); A61K 8/99 (2013.01); A61K 9/0014 (2013.01); A61K 9/0043 (2013.01); A61K 9/0046 (2013.01); A61K 9/0048 (2013.01); A61K 9/007 (2013.01); A61K 35/644 (2013.01); A61K 35/74 (2013.01); A61K 35/744 (2013.01); A61K 35/747 (2013.01); A61K 39/092 (2013.01); A61K 45/06 (2013.01); A61K 47/10 (2013.01); A61Q 11/00 (2013.01); A61Q 17/005 (2013.01); A61Q 19/007 (2013.01); A61Q 19/10 (2013.01); C12N 1/20 (2013.01); C12Q 1/04 (2013.01); C12Q 1/18 (2013.01); A61K 36/61 (2013.01); A61K 39/39 (2013.01); A61K 2300/00 (2013.01); A61K 2800/78 (2013.01); A61K 2800/782 (2013.01); G01N 2333/315 (2013.01); G01N 2333/335 (2013.01); Y02A 50/30 (2018.01)] 4 Claims
 
1. A method for the control of biofilm on an inanimate surface wherein said method reduces biofilm attachment; inhibits biofilm growth; disrupts a biofilm matrix; prevents, inhibits, and/or disrupts secretion and/or release of biofilm extracellular factors; and/or prevents, inhibits, and/or disrupts quorum-sensing mechanisms of a biofilm; wherein said method comprises applying to the inanimate surface a composition comprising microbial biofilm cellular mass, exopolysaccharides, and a biologically-active agent produced by the microbial biofilm.