US 12,342,819 B2
Elasnin, a bacteriostatic agent that has potent antibiofilm activities against both mono- and multi-species biofilm
Pei-Yuan Qian, Hong Kong (CN); Lexin Long, Hong Kong (CN); Yongxin Li, Hong Kong (CN); Ruojun Wang, Hong Kong (CN); and Ho Yin Chiang, Hong Kong (CN)
Assigned to The Hong Kong University of Science and Technology, Hong Kong (CN); and China Ocean Mineral Resources R&D Association, Beijing (CN)
Filed by The Hong Kong University of Science and Technology, Hong Kong (CN); and China Ocean Mineral Resources R&D Association (COMRA), Beijing (CN)
Filed on Aug. 21, 2020, as Appl. No. 16/999,437.
Claims priority of provisional application 62/890,786, filed on Aug. 23, 2019.
Prior Publication US 2021/0051956 A1, Feb. 25, 2021
Int. Cl. A61K 38/14 (2006.01); A01N 43/16 (2006.01); A01N 63/28 (2020.01); A61K 35/74 (2015.01); A61P 31/04 (2006.01); C02F 1/50 (2023.01); C09D 5/14 (2006.01); C09D 5/16 (2006.01)
CPC A01N 43/16 (2013.01) [C09D 5/1625 (2013.01)] 13 Claims
 
1. An anti-biofilm composition comprising elasnin and one or more antimicrobial compounds, wherein the composition exhibits anti-biofilm activity and comprises elasnin at a concentration of 1.25 to 2.5 μg/ml and the one or more antimicrobial compounds at a concentration of 1.25 to 2.5 μg/ml, wherein the composition is selected from the group consisting of acrylic-based, latex-based, and oil-based anti-biofilm compositions.