US 12,019,039 B2
Sensor systems, devices, and methods for continuous glucose monitoring
Keith Nogueira, Mission Hills, CA (US); Taly G. Engel, Los Angeles, CA (US); Xiaolong Li, Porter Ranch, CA (US); Bradley C. Liang, Bloomfield Hills, MI (US); Rajiv Shah, Rancho Palos Verdes, CA (US); Jaeho Kim, Redmond, WA (US); Mike C. Liu, Walnut, CA (US); Andy Y. Tsai, Pasadena, CA (US); Andrea Varsavsky, Santa Monica, CA (US); and Fei Yu, Chatsworth, CA (US)
Assigned to MEDTRONIC MINIMED, INC., Northridge, CA (US)
Filed by MEDTRONIC MINIMED, INC., Northridge, CA (US)
Filed on Oct. 11, 2018, as Appl. No. 16/158,043.
Application 16/158,043 is a division of application No. 14/980,185, filed on Dec. 28, 2015, abandoned.
Prior Publication US 2019/0041345 A1, Feb. 7, 2019
Int. Cl. G01N 27/02 (2006.01); G01N 33/487 (2006.01); G01N 33/49 (2006.01)
CPC G01N 27/026 (2013.01) [G01N 33/48707 (2013.01); G01N 33/49 (2013.01)] 6 Claims
OG exemplary drawing
 
1. A method of operating a glucose sensor, the glucose sensor including physical sensor electronics, a microcontroller, and a working electrode, and being in operational contact with a display device configured to display glucose sensor data to a user, the method comprising:
sensing, by the physical sensor electronics, a glucose level of a user of the glucose sensor;
generating, by the microcontroller, glucose sensor data to be displayed on the display device based on the glucose level sensed by the physical sensor electronics;
performing, by the microcontroller, an electrochemical impedance spectroscopy (EIS) procedure to continuously generate real impedance values for the working electrode;
filtering, by the microcontroller, the real impedance values;
analyzing the real impedance values by the microcontroller to determine a stability of the real impedance values;
based on the determined stability, comparing, by the microcontroller, the real impedance values to a first threshold impedance value;
based on the comparison, determining, by the microcontroller, whether the glucose sensor data to be displayed on the display device is valid;
displaying, by the microcontroller, the glucose sensor data on the display device in response to a determination that the glucose sensor data is valid;
blanking, by the microcontroller, the glucose sensor data from the display device in response to a determination that the glucose sensor data is invalid;
comparing the real impedance values to a second threshold impedance value; and
terminating, by the microcontroller, the glucose sensor in response to the real impedance values continuously exceeding the second threshold impedance value for a predetermined period of time.