	US 12,017,998 B1
	5-(2,4,5-tris(4-chlorophenyl)-1H-imidazol-1-yl)pentanoic acid as an antimicrobial compound
Hany Mohamed Abd El-Lateef Ahmed, Al-Ahsa (SA); Mai Mostafa Khalaf Ali, Al-Ahsa (SA); Antar Ahmed Abdelhamid Ahmed, Sohag (EG); and Amer A. Amer, Sohag (EG)
Assigned to KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed by KING FAISAL UNIVERSITY, Al-Ahsa (SA)
Filed on Feb. 8, 2024, as Appl. No. 18/437,229.
Application 18/437,229 is a division of application No. 18/494,734, filed on Oct. 25, 2023.
Int. Cl. C07D 233/64 (2006.01); A61P 31/04 (2006.01); A61P 31/10 (2006.01)

CPC C07D 233/64 (2013.01) [A61P 31/04 (2018.01); A61P 31/10 (2018.01)]

6 Claims

1. A method of making a 5-(2,4,5-tris(4-chlorophenyl)-1H-imidazol-1-yl)pentanoic acid compound, the method comprising:

mixing 1,2-bis(4-chlorophenyl)ethane-1,2-dione, 4-chlorobenzaldehyde, 5-aminopentanoic acid, and ammonium acetate in pyridinium ionic liquid to obtain a solution;

irradiating the solution followed by cooling to room temperature to obtain a formed precipitate;

purifying the formed precipitate by filtering and recrystallization using ethanol; and

obtaining the 5-(2,4,5-tris(4-chlorophenyl)-1H-imidazol-1-yl)pentanoic acid compound.