US 11,685,742 B2
Anti-tumor compound and preparation method and use thereof
Yu Zhang, Shanghai (CN); Zhongyuan Zhu, Shanghai (CN); Haiqing Hua, Shanghai (CN); Bing Li, Shanghai (CN); Jian Li, Shanghai (CN); Shengchao Lin, Shanghai (CN); Xi Li, Shanghai (CN); and Hongxia Shen, Shanghai (CN)
Assigned to DUALITY BIOLOGICS (SUZHOU) CO., LTD., Shanghai (CN)
Filed by DUALITY BIOLOGICS (SUZHOU) CO., LTD., Shanghai (CN)
Filed on May 26, 2022, as Appl. No. 17/825,090.
Application 17/825,090 is a continuation of application No. PCT/CN2021/121721, filed on Sep. 29, 2021.
Claims priority of application No. 202011061580.7 (CN), filed on Sep. 30, 2020.
Prior Publication US 2023/0086097 A1, Mar. 23, 2023
Int. Cl. C07D 491/22 (2006.01); A61P 35/00 (2006.01)
CPC C07D 491/22 (2013.01) [A61P 35/00 (2018.01)] 8 Claims
 
1. A compound or a tautomer, a mesomer, a racemate, an enantiomer or a diastereoisomer thereof, or a mixture thereof, or a pharmaceutically acceptable salt thereof, wherein the compound comprises a structure shown as formula below:

OG Complex Work Unit Chemistry
wherein, R2 is —O—, and R2 is used for direct or indirect linking to a ligand.