US 12,339,262 B2
Analysis assistance device, method, and program for searching for an analysis condition for use with a liquid chromatography system
Satoru Watanabe, Kyoto (JP)
Assigned to SHIMADZU CORPORATION, Kyoto (JP)
Filed by SHIMADZU CORPORATION, Kyoto (JP)
Filed on Apr. 14, 2021, as Appl. No. 17/230,723.
Claims priority of application No. 2020-080822 (JP), filed on Apr. 30, 2020.
Prior Publication US 2021/0341441 A1, Nov. 4, 2021
Int. Cl. G01N 30/86 (2006.01); G01N 30/02 (2006.01); G01N 30/88 (2006.01)
CPC G01N 30/8658 (2013.01) [G01N 30/8675 (2013.01); G01N 2030/027 (2013.01); G01N 2030/889 (2013.01)] 5 Claims
OG exemplary drawing
 
1. An analysis assistance device for searching for an optimal analysis condition for use with a liquid chromatography system, the device comprising a processor configured to:
receive a plurality of analysis conditions, wherein each of the plurality of analysis conditions includes values for a plurality of analysis parameters;
obtain a measurement data set comprising measurement data from the liquid chromatography system for each of the plurality of analysis conditions;
calculate a measurement quality data set comprising measurement quality data for each of the measurement data of the obtained measurement data set;
estimate as distribution data a distribution of the calculated measurement quality data set relative to the plurality of analysis parameters; and
display as a design space a region of the distribution data where the measurement quality data is greater than or equal to a predetermined threshold value, wherein:
the design space includes a plurality of boundaries and the plurality of analysis parameters as axes, and
the design space is displayed such that when the design space includes a change in the measurement quality data that is larger than a change in the plurality of analysis parameters:
the region is enlarged as an enlargement region; and
the enlargement region is based on a spacing between each of boundaries, such that a small spacing between each of the boundaries compared to each spacing of an other area along a direction of an axis of the design space results in a large spacing in the enlargement region by cutting off at least part of the enlarged area in the design space of the measurement quality data.