US 12,338,230 B2
Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders
Jason Allan Wiles, Madison, CT (US); Avinash S. Phadke, Branford, CT (US); Milind Deshpande, Madison, CT (US); Atul Agarwal, Hamden, CT (US); Dawei Chen, Guilford, CT (US); Venkat Rao Gadhachanda, Hamden, CT (US); Akihiro Hashimoto, Branford, CT (US); Godwin Pais, Hamden, CT (US); Qiuping Wang, Bethany, CT (US); Xiangzhu Wang, Branford, CT (US); and William Greenlee, Teaneck, NJ (US)
Assigned to Achillion Pharmaceuticals, Inc., Boston, MA (US)
Filed by Achillion Pharmaceuticals, Inc., Boston, MA (US)
Filed on Jan. 22, 2024, as Appl. No. 18/418,560.
Application 18/418,560 is a continuation of application No. 17/835,098, filed on Jun. 8, 2022, granted, now 11,926,617.
Application 17/835,098 is a continuation of application No. 16/867,475, filed on May 5, 2020, granted, now 11,407,738, issued on Aug. 9, 2022.
Application 16/867,475 is a continuation of application No. 15/905,524, filed on Feb. 26, 2018, granted, now 10,662,175, issued on May 26, 2020.
Application 15/905,524 is a continuation of application No. PCT/US2016/048788, filed on Aug. 25, 2016.
Claims priority of provisional application 62/210,116, filed on Aug. 26, 2015.
Prior Publication US 2024/0199583 A1, Jun. 20, 2024
Int. Cl. C07D 407/14 (2006.01); A61P 1/16 (2006.01); A61P 29/00 (2006.01); A61P 37/00 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/10 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 487/22 (2006.01); C07D 493/04 (2006.01); C07D 513/04 (2006.01); C07D 519/00 (2006.01); C07F 9/6558 (2006.01)
CPC C07D 403/04 (2013.01) [A61P 1/16 (2018.01); A61P 29/00 (2018.01); A61P 37/00 (2018.01); C07D 401/14 (2013.01); C07D 403/10 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 407/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 487/22 (2013.01); C07D 493/04 (2013.01); C07D 513/04 (2013.01); C07D 519/00 (2013.01); C07F 9/65583 (2013.01)] 16 Claims
 
1. A compound selected from:

OG Complex Work Unit Chemistry

OG Complex Work Unit Chemistry

OG Complex Work Unit Chemistry

OG Complex Work Unit Chemistry

OG Complex Work Unit Chemistry

OG Complex Work Unit Chemistry

OG Complex Work Unit Chemistry
or a pharmaceutically acceptable salt thereof.