US 12,337,324 B2
Microreactor array platform
Peter Wiktor, Phoenix, AZ (US)
Assigned to ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY, Scottsdale, AZ (US)
Filed by Peter Wiktor, Phoenix, AZ (US)
Filed on Oct. 13, 2020, as Appl. No. 17/069,315.
Application 17/069,315 is a continuation of application No. 15/114,894, granted, now 10,850,278, previously published as PCT/US2015/013198, filed on Jan. 28, 2015.
Claims priority of provisional application 61/933,054, filed on Jan. 29, 2014.
Prior Publication US 2021/0039091 A1, Feb. 11, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. B01L 3/00 (2006.01); B01J 19/00 (2006.01); B01L 3/02 (2006.01)
CPC B01L 3/50853 (2013.01) [B01J 19/0046 (2013.01); B01L 3/50851 (2013.01); B01J 2219/00286 (2013.01); B01J 2219/00317 (2013.01); B01J 2219/00396 (2013.01); B01J 2219/00414 (2013.01); B01J 2219/00416 (2013.01); B01J 2219/00418 (2013.01); B01L 3/0282 (2013.01); B01L 3/0293 (2013.01); B01L 2200/025 (2013.01); B01L 2200/0642 (2013.01); B01L 2200/0684 (2013.01); B01L 2200/0689 (2013.01); B01L 2200/141 (2013.01); B01L 2200/142 (2013.01); B01L 2200/16 (2013.01); B01L 2300/044 (2013.01); B01L 2300/046 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0819 (2013.01); B01L 2300/0822 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/161 (2013.01); B01L 2300/165 (2013.01); B01L 2400/0409 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/049 (2013.01); B01L 2400/0605 (2013.01); B01L 2400/0666 (2013.01); B01L 2400/0683 (2013.01); B01L 2400/0688 (2013.01)] 12 Claims
OG exemplary drawing
 
1. A microreactor array platform comprising:
a base having a wall having an internal surface defining a cavity in the base and a reagent inlet port;
a substrate positioned within the cavity, the substrate having a flat upper surface;
a sealing film positioned above the substrate and having a first surface and an opposite second surface having a closer proximity to the substrate than the first surface, wherein the sealing film defines an array of microreactors patterned on the second surface and is configured to movably seal the array of microreactors against the upper surface of the substrate;
the second surface of the sealing film and the upper surface of the substrate defining a reagent gap providing a fluid path between the microreactor array and the substrate when the second surface of the sealing film is in spaced relationship with the upper surface of the substrate;
an injector for delivering a reagent into the reagent gap through the reagent inlet port; and
an applicator for directing a sealing liquid against the first surface of the sealing film through a sealing liquid inlet port positioned above the sealing film,
wherein the sealing film is impervious to fluids, providing a separation between the reagent and the sealing liquid.