| CPC A61N 5/1031 (2013.01) [A61N 5/1001 (2013.01); A61N 5/1045 (2013.01); A61N 5/1049 (2013.01); A61N 5/1065 (2013.01); A61N 5/1067 (2013.01); A61N 5/1069 (2013.01); A61N 5/107 (2013.01); A61N 5/1081 (2013.01); A61N 2005/1019 (2013.01); A61N 5/1036 (2013.01); A61N 5/1039 (2013.01); A61N 2005/1041 (2013.01); A61N 5/1075 (2013.01)] | 20 Claims |

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1. A method for updating a treatment plan fluence map, the method comprising:
acquiring PET imaging data originating from a target region using PET detectors;
identifying a location of the target region from the acquired PET imaging data; and
updating a treatment plan fluence map for irradiating the target region using the identified location, wherein updating the treatment plan fluence map comprises scaling a planned fluence using one or more of a normalization factor, a dampening factor, and a weighting factor.
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