US 12,337,183 B2
Systems and methods for reducing neurostimulation electrode configuration and parameter search space
Lisa Denise Moore, Glendale, CA (US); and Mahsa Malekmohammadi, Sherman Oaks, CA (US)
Assigned to Boston Scientific Neuromodulation Corporation, Valencia, CA (US)
Filed by Boston Scientific Neuromodulation Corporation, Valencia, CA (US)
Filed on Apr. 26, 2022, as Appl. No. 17/729,456.
Claims priority of provisional application 63/186,590, filed on May 10, 2021.
Prior Publication US 2022/0355114 A1, Nov. 10, 2022
Int. Cl. A61N 1/36 (2006.01); A61N 1/02 (2006.01); A61N 1/05 (2006.01)
CPC A61N 1/36185 (2013.01) [A61N 1/025 (2013.01); A61N 1/0551 (2013.01); A61N 1/36135 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A system for providing electrostimulation to a patient, comprising:
an implantable stimulator configured to provide electrostimulation to a neural target of the patient via a lead comprising a plurality of electrodes; and
a programming device communicatively coupled to the implantable stimulator, the programming device including a controller configured to:
receive electrode position information of the plurality of electrodes relative to an anatomical region of interest at or about the neural target, or physiological signals respectively sensed by the plurality of electrodes;
identify a search space of electrode configurations and parameter values for the lead with respect to the neural target using the received electrode position information and the sensed physiological signals, the search space comprising a subset of electrodes selected from the plurality of electrodes and stimulation parameter values or value ranges associated with the subset of electrodes;
determine a target stimulation setting based at least on a clinical response to electrostimulation delivered using electrodes and stimulation parameter values from the identified search space; and
generate a control signal to the implantable stimulator and cause delivery of electrostimulation to the patient in accordance with the determined target stimulation setting,
wherein to identify the search space, the controller is configured to:
identify, from the plurality of electrodes, a first candidate set of electrodes using the received electrode position information but without using the received physiological signals;
identify, from the plurality of electrodes, a second candidate set of electrodes using the received physiological signals but without using the received electrode position information; and
determine the subset of electrodes for inclusion in the search space based at least on a discrepancy metric between the first candidate set of electrodes and the second candidate set of electrodes.