US 12,336,978 B2
Pharmaceutical composition containing amlodipine, chlorthalidone, and amiloride and application thereof
Guangliang Chen, Guangdong (CN); Duo Yu, Guangdong (CN); Jie Bai, Guangdong (CN); Minqing Tian, Guangdong (CN); Ping Chen, Guangdong (CN); and Xiping Xu, Guangdong (CN)
Assigned to SHENZHEN AUSA PHARMED CO., LTD., Shenzhen (CN); and SHENZHEN AUSA PHARMACEUTICAL CO., LTD., Shenzhen (CN)
Filed by SHENZHEN AUSA PHARMED CO., LTD., Guangdong (CN); and SHENZHEN AUSA PHARMACEUTICAL CO., LTD., Guangdong (CN)
Filed on Sep. 29, 2021, as Appl. No. 17/489,575.
Application 17/489,575 is a continuation of application No. PCT/CN2020/083332, filed on Apr. 3, 2020.
Claims priority of application No. 201910274749.8 (CN), filed on Apr. 8, 2019.
Prior Publication US 2022/0079920 A1, Mar. 17, 2022
Int. Cl. A61K 31/4035 (2006.01); A61K 31/4418 (2006.01); A61K 31/4965 (2006.01)
CPC A61K 31/4035 (2013.01) [A61K 31/4418 (2013.01); A61K 31/4965 (2013.01)] 18 Claims
 
1. A pharmaceutical composition for treating resistant hypertension, consisting of:
(a) 2.5-10 mg of amlodipine;
(b) 12.5-100 mg of chlorthalidone;
(c) 2.5-20 mg of amiloride; and
(d) a pharmaceutically acceptable carrier.