| CPC A61F 9/0079 (2013.01) [A61N 5/0613 (2013.01); A61N 5/0616 (2013.01); A61N 5/062 (2013.01); A61N 5/0622 (2013.01); A61N 5/0624 (2013.01); A61F 2009/00863 (2013.01); A61N 2005/0643 (2013.01); A61N 2005/0648 (2013.01); A61N 2005/0651 (2013.01); A61N 2005/0659 (2013.01); A61N 2005/0662 (2013.01); A61N 5/067 (2021.08)] | 26 Claims |

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1. A wearable device for delivery of photobiomodulation (PBM) to retinal tissue of an eye of a patient, the wearable device comprising:
a frame comprising a front piece and at least one affixation element attached to the front piece, wherein the front piece is configured to be positioned in front of the eye of the patient;
at least one first light source disposed within or on the at least one affixation element and configured to produce light in a first light beam having a first PBM wavelength comprising near infrared (NIR) light;
at least one second light source disposed within or on the at least one affixation element and configured to produce light in a second light beam having a second PBM wavelength,
wherein the second PBM wavelength differs from the first PBM wavelength by at least 25 nm, and
wherein at least a portion of each of the first light beam and the second light beam is directed toward the front piece of the frame;
a diffuser configured to homogenize the light in the first light beam or the second light beam, or in both the first light beam and the second light beam, such that an energy density profile of the light is evenly distributed among a range of emission angles; and
at least one light directing element disposed within or on the front piece of the frame and configured to receive and redirect the at least a portion of each of the first light beam having the first PBM wavelength and the second light beam having the second PBM wavelength toward the retinal tissue of the eye of the patient when the patient is wearing the wearable device.
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