US 12,336,858 B2
Methods for identifying the boundaries of a blood vessel
Jayaraj Joseph, Chennai (IN); Raj Kiran Vangapandu, Chennai (IN); Nabeel Pilaparambil Mashood, Chennai (IN); and Mohanasankar Sivaprakasam, Chennai (IN)
Assigned to HEALTHCARE TECHNOLOGY INNOVATION CENTRE, Chennai (IN); and INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IIT MADRAS), Chennai (IN)
Appl. No. 17/996,722
Filed by Healthcare Technology Innovation Centre, Chennai (IN); and Indian Institute of Technology Madras (IIT Madras), Chennai (IN)
PCT Filed Apr. 27, 2021, PCT No. PCT/IN2021/050411
§ 371(c)(1), (2) Date Oct. 20, 2022,
PCT Pub. No. WO2021/220300, PCT Pub. Date Nov. 4, 2021.
Claims priority of application No. 202041017854 (IN), filed on Apr. 27, 2020.
Prior Publication US 2023/0210497 A1, Jul. 6, 2023
Int. Cl. A61B 8/00 (2006.01)
CPC A61B 8/44 (2013.01) [A61B 8/5207 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A method for identifying boundaries of a blood vessel in a human body, the method comprising:
receiving, by a vessel-wall-monitoring device (100), a plurality of ultrasound echo signals comprising a plurality of ultrasound frames from an ultrasound transducer (110), wherein the plurality of ultrasound echo signals are transmitted to the ultrasound transducer (110) from locations of the blood vessel;
extracting, by the vessel-wall-monitoring device (100), at least two consecutive ultrasound frames from the plurality of ultrasound echo signals;
determining, by the vessel-wall-monitoring device (100), a shift between the at least two consecutive ultrasound frames by comparing the at least two consecutive ultrasound frames, wherein comparing the at least two consecutive ultrasound frames is used to determine a phase change waveform between the at least two consecutive ultrasound frames, determining the phase change waveform comprises:
determining a quadrature phase counterpart corresponding to each of the at least two consecutive ultrasound frames by applying Hilbert transform on the each of the at least two ultrasound frames,
generating a single sideband (SSB) signal corresponding to each of the at least two ultrasound frames by adding the each of the at least two consecutive ultrasound frames to the corresponding quadrature phase counterpart,
constructing continuous phase waveforms of each of the at least two consecutive ultrasound frames by performing a tangent inverse operation on the SSB signal corresponding to each of the at least two consecutive ultrasound frames, and
determining the phase change waveform by subtracting the continuous phase waveforms of each of the at least two ultrasound frames; and
identifying, by the vessel-wall-monitoring device (100), the boundaries of the blood vessel, wherein identifying the boundaries comprises identifying a proximal wall and a distal wall of the blood vessel based on the determined shift between the at least two consecutive ultrasound frames.