US 12,013,389 B2
Method of evaluating pathological conditions of heart failure
Shingo Takada, Sapporoshi (JP); Satoshi Maekawa, Sapporoshi (JP); Takashi Yokota, Sapporoshi (JP); Ryosuke Shirakawa, Sapporoshi (JP); and Hisataka Sabe, Sapporoshi (JP)
Assigned to NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY, Hokkaido (JP)
Appl. No. 17/276,782
Filed by NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY, Hokkaido (JP)
PCT Filed Jun. 28, 2019, PCT No. PCT/JP2019/025885
§ 371(c)(1), (2) Date Mar. 16, 2021,
PCT Pub. No. WO2020/059242, PCT Pub. Date Mar. 26, 2020.
Claims priority of provisional application 62/733,662, filed on Sep. 20, 2018.
Prior Publication US 2021/0349079 A1, Nov. 11, 2021
Int. Cl. G01N 33/50 (2006.01); A61K 31/197 (2006.01); A61K 31/7076 (2006.01)
CPC G01N 33/5091 (2013.01) [A61K 31/197 (2013.01); A61K 31/7076 (2013.01)] 8 Claims
 
1. A heart failure treatment method, comprising
increasing an amount of succinyl-CoA in cardiomyocytes for an animal with heart failure.