US 12,013,367 B2
Monolithic 3D integrated circuit for gas sensing and method of making and system using
Max Shulaker, Weston, MA (US); and Mindy Deanna Bishop, Cambridge, MA (US)
Assigned to Massachusetts Institute of Technology, Cambridge, MA (US)
Filed by Massachusetts Institute of Technology, Cambridge, MA (US)
Filed on Dec. 16, 2022, as Appl. No. 18/067,455.
Application 18/067,455 is a division of application No. 16/973,249, granted, now 11,561,195, previously published as PCT/US2019/036006, filed on Jun. 7, 2019.
Claims priority of provisional application 62/682,497, filed on Jun. 8, 2018.
Prior Publication US 2023/0204536 A1, Jun. 29, 2023
Int. Cl. G01N 27/414 (2006.01); G01N 33/497 (2006.01)
CPC G01N 27/4141 (2013.01) [G01N 27/4146 (2013.01); G01N 33/497 (2013.01); G01N 2033/4977 (2013.01)] 16 Claims
OG exemplary drawing
 
1. A method of diagnosing ventilator-associated pneumonia (VAP) with a monolithic, three-dimensional (3D) integrated circuit (IC) comprising carbon nanotube field-effect transistors (CNFETs) arranged in a sensing layer, a memory layer operably coupled to the sensing layer, and a processing layer operably coupled to the memory layer, the method comprising:
sensing an exhalation of a patient with the CNFETs;
writing data in parallel from the CNFETs to memory elements in the memory layer;
transferring the data in parallel from the memory elements to processing elements in the processing layer;
detecting, with the processing elements, at least one volatile organic compound (VOC) representative of VAP in the exhalation of the patient based on the data; and
diagnosing the patient as having VAP based on the at least one VOC detected in the exhalation of the patient.