US 12,012,434 B2
Mutant transporters for bacterial uptake of terephthalic acid
Christopher W. Johnson, Denver, CO (US); Gregg Tyler Beckham, Golden, CO (US); Isabel Pardo Mendoza, Dos Hermanas (ES); and Ellen Lee Neidle, Dacula, GA (US)
Assigned to Alliance for Sustainable Energy, LLC, Golden, CO (US); and University of Georgia Research Foundation, Inc., Athens, GA (US)
Filed by Alliance for Sustainable Energy, LLC, Golden, CO (US); and University of Georgia Research Foundation, Inc., Athens, GA (US)
Filed on Sep. 13, 2021, as Appl. No. 17/472,936.
Claims priority of provisional application 63/077,173, filed on Sep. 11, 2020.
Prior Publication US 2022/0089654 A1, Mar. 24, 2022
Int. Cl. C07K 14/195 (2006.01)
CPC C07K 14/195 (2013.01) 18 Claims
 
1. A non-naturally occurring microorganism comprising:
a gene encoding a MucK transporter protein; and
a deletion of an endogenous gene encoding a transcriptional regulator, wherein:
the microorganism is capable of catabolizing terephthalic acid (TPA).