US 12,012,430 B2
Method for preparing liquid maltitol and liquid polyols from a raffinate including maltitol
Yanhui Yao, Quzhou (CN); Xinfeng Han, Quzhou (CN); Fuan Wan, Quzhou (CN); Hang Yue, Quzhou (CN); Weixing Shen, Quzhou (CN); Haojun Dai, Quzhou (CN); Mingqian Yang, Quzhou (CN); and Mian Li, Quzhou (CN)
Assigned to ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD., Quzhou (CN)
Filed by ZHEJIANG HUAKANG PHARMACEUTICAL CO., LTD., Zhejiang (CN)
Filed on Sep. 18, 2023, as Appl. No. 18/469,518.
Application 18/469,518 is a continuation of application No. PCT/CN2022/133110, filed on Nov. 21, 2022.
Claims priority of application No. 202111588188.2 (CN), filed on Dec. 23, 2021.
Prior Publication US 2024/0010667 A1, Jan. 11, 2024
Int. Cl. C07H 15/04 (2006.01)
CPC C07H 15/04 (2013.01) 5 Claims
 
1. A method for preparing liquid maltitol and liquid polyols from a raffinate including maltitol, comprising:
obtaining a hydrogenated liquid by hydrogenating a pre-treated raffinate including maltitol, the pre-treated raffinate having a refractive index of 48%-54%, a maltitol content of 15%-40%, a sorbitol content of 25%-40%, and an oligosaccharide alcohol content of 35%˜45%;
obtaining a post-treated liquid by post-treatment of the hydrogenated liquid to remove impurities;
obtaining a dilute liquid and a concentrated maltitol solution by membrane-separation of the post-treated liquid; and
using the dilute liquid as the liquid polyols, and obtaining the liquid maltitol by mixing the concentrated maltitol solution with a prepared maltitol solution with a maltitol content of over 50%, wherein the liquid maltitol has a maltitol content greater than or equal to 50%, wherein
the pre-treatment of the raffinate including maltitol includes membrane concentration or evaporative concentration, first decolorization treatment, and evaporation treatment, and the post-treatment of the hydrogenated liquid includes secondary decolorization treatment and ion exchange treatment.