US 12,011,612 B2
Systems and methods for robust radiation treatment planning
Jingjie Zhou, Shanghai (CN); and Supratik Bose, Houston, TX (US)
Assigned to SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD., Shanghai (CN)
Filed by SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD., Shanghai (CN)
Filed on Nov. 24, 2020, as Appl. No. 17/102,472.
Application 17/102,472 is a continuation of application No. PCT/CN2019/084548, filed on Apr. 26, 2019.
Prior Publication US 2021/0077827 A1, Mar. 18, 2021
Int. Cl. A61N 5/10 (2006.01); G06T 7/11 (2017.01); G06T 7/136 (2017.01); G06T 7/149 (2017.01); G06T 7/33 (2017.01); G16H 30/40 (2018.01)
CPC A61N 5/103 (2013.01) [G06T 7/11 (2017.01); G06T 7/136 (2017.01); G06T 7/149 (2017.01); G06T 7/337 (2017.01); G16H 30/40 (2018.01); G06T 2207/20104 (2013.01); G06T 2207/30096 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A method for generating a radiation treatment plan for a treatment volume of a subject, implemented on at least one machine each of which includes at least one processor and at least one storage device, the method comprising:
retrieving a planning image of the treatment volume, the planning image including a plurality of first voxels, each of the plurality of first voxels corresponding to an initial dose value;
retrieving a treatment image that represents at least part of the treatment volume, the treatment image including a plurality of second voxels;
registering the treatment image with the planning image to obtain a mapping relationship between the plurality of second voxels in the treatment image and the plurality of first voxels in the planning image;
for each of at least one of the plurality of second voxels,
determining a corresponding first voxel of the second voxel based on the mapping relationship;
determining a set of first voxels, a distance between each first voxel in the set of first voxels and the corresponding first voxel being smaller than a distance threshold;
determining, among the set of first voxels, at least one first voxel as at least one reference voxel corresponding to the second voxel, a first feature value of each of the at least one first voxel being equal to or close to a second feature value of the second voxel; and
determining a dose value of the second voxel based on the at least one initial dose value of the at least one reference voxel; and
generating a radiation treatment plan by updating an original treatment plan associated with the planning image based at least part on the dose value corresponding to the at least one second voxel.