US 12,011,303 B2
Real-time pain detection and pain management system
Lee-Kui Chen, Taipei (TW); and Tzu-Kuei Shen, Taipei (TW)
Assigned to CJSHINE TECHNOLOGY COMPANY LTD., Taipei (TW)
Filed by CJSHINE TECHNOLOGY COMPANY LTD., Taipei (TW)
Filed on Nov. 29, 2019, as Appl. No. 16/699,465.
Claims priority of provisional application 62/894,532, filed on Aug. 30, 2019.
Claims priority of provisional application 62/772,891, filed on Nov. 29, 2018.
Prior Publication US 2020/0170581 A1, Jun. 4, 2020
Int. Cl. A61B 5/00 (2006.01); A61B 5/024 (2006.01); A61B 5/349 (2021.01); A61M 19/00 (2006.01); G16H 20/13 (2018.01); G16H 20/17 (2018.01); G16H 40/67 (2018.01); A61N 1/36 (2006.01)
CPC A61B 5/7278 (2013.01) [A61B 5/02405 (2013.01); A61B 5/349 (2021.01); A61B 5/4356 (2013.01); A61B 5/4824 (2013.01); A61B 5/4839 (2013.01); A61B 5/7225 (2013.01); A61B 5/742 (2013.01); A61M 19/00 (2013.01); G16H 20/13 (2018.01); G16H 20/17 (2018.01); G16H 40/67 (2018.01); A61N 1/36021 (2013.01); A61N 1/36031 (2017.08)] 9 Claims
OG exemplary drawing
 
6. A method for management of pain in a subject, comprising:
acquiring heart-related biomedical signals in said subject,
transforming the acquired heart-related biomedical signals during a given period of time into signal data for measurement of pain by performing frequency domain conversion for each given period of time of heart-related biomedical signals to form frequency domain signal data,
analyzing the frequency domain signal data in relation to pre-determined modeled data having relationship between frequency domain heart-related signals and pain, wherein the pre-determined modeled data includes at least a pain model which is defined by a peak-shaped profile in frequency domain data and a non-pain model which is defined by a flat profile in frequency domain data, generating an index of pain using the results of the analysis, and determining a pain status of the subject based on the index of pain, and
delivering an analgesic agent to the subject based on the pain status and the index of pain.