US 12,011,294 B2
Continuous analyte monitoring system with microneedle array
Alan Campbell, San Diego, CA (US); Sirilak Sattayasamitsathit, San Diego, CA (US); Jared Rylan Tangney, Encinitas, CA (US); Thomas Arnold Peyser, Menlo Park, CA (US); and Joshua Ray Windmiller, San Diego, CA (US)
Assigned to Biolinq Incorporated, San Diego, CA (US)
Filed by Biolinq Incorporated, San Diego, CA (US)
Filed on Dec. 21, 2022, as Appl. No. 18/086,543.
Application 18/086,543 is a continuation of application No. PCT/US2021/043786, filed on Jul. 29, 2021.
Claims priority of provisional application 63/058,275, filed on Jul. 29, 2020.
Prior Publication US 2023/0190147 A1, Jun. 22, 2023
Int. Cl. A61B 5/00 (2006.01); A61B 5/145 (2006.01); A61B 5/1486 (2006.01)
CPC A61B 5/685 (2013.01) [A61B 5/0022 (2013.01); A61B 5/14514 (2013.01); A61B 5/14532 (2013.01); A61B 5/14546 (2013.01); A61B 5/14865 (2013.01); A61B 5/6833 (2013.01); A61B 5/742 (2013.01)] 88 Claims
OG exemplary drawing
 
1. A microneedle array for use in sensing an analyte, comprising:
a first solid, lumen-free microneedle comprising a working electrode, wherein the working electrode comprises a first electrode material and a biorecognition layer on the first electrode material, wherein the biorecognition layer comprises a biorecognition element configured to react with the analyte, wherein a distal tip of the first solid, lumen-free microneedle is insulated;
a second, lumen-free solid microneedle comprising a counter electrode, wherein the counter electrode comprises a second electrode material; and
a third solid, lumen-free microneedle comprising a reference electrode, wherein the reference electrode comprises a third electrode material and a redox-couple layer on the third electrode material, and
wherein a redox reaction occurs between the working electrode on the first solid, lumen-free microneedle and the counter electrode on the second solid, lumen-free microneedle.