	US 12,011,000 B2
	Affinity molecules and methods for their use
Heba Mohamed Yassen Abdelgaffar, Knoxville, TN (US); Constanze Hahnfeld, Einbeck (DE); Juan Luis Jurat-Fuentes, Knoxville, TN (US); Erik Jongedijk, Einbeck (DE); Jeffrey M. Staub, Wildwood, MO (US); and Stefan Meldau, Einbeck (DE)
Assigned to IMPETUS AGRICULTURE, INC., St. Louis, MO (US)
Filed by IMPETUS AGRICULTURE, INC., St. Louis, MO (US)
Filed on Jul. 3, 2023, as Appl. No. 18/346,437.
Application 18/346,437 is a continuation in part of application No. PCT/US2022/017993, filed on Feb. 25, 2022.
Claims priority of provisional application 63/241,896, filed on Sep. 8, 2021.
Claims priority of provisional application 63/133,386, filed on Jan. 3, 2021.
Prior Publication US 2024/0041049 A1, Feb. 8, 2024
Int. Cl. A01N 63/50 (2020.01); A01P 7/04 (2006.01); C07K 14/325 (2006.01); C07K 16/12 (2006.01); C07K 16/28 (2006.01)

CPC A01N 63/50 (2020.01) [A01P 7/04 (2021.08); C07K 14/325 (2013.01); C07K 16/1278 (2013.01); C07K 16/28 (2013.01); C07K 2317/31 (2013.01); C07K 2317/569 (2013.01); C07K 2317/92 (2013.01); C07K 2319/55 (2013.01)]

14 Claims

1. A recombinant nucleic acid molecule comprising a polynucleotide sequence encoding an affinity molecule comprising a first single domain antibody comprising the complementarity determining region 1 (CDR1) amino acid sequence of SEQ ID NO: 138, the complementarity determining region 2 (CDR2) amino acid sequence of SEQ ID NO: 139, and the complementarity determining region 3 (CDR3) amino acid sequence of SEQ ID NO: 140 or 141, wherein the affinity molecule binds an insect gut nutrient amino acid transporter protein.