US 12,334,322 B2
Systems and methods for isolating a target ion in an ion trap
Robert Graham Cooks, West Lafayette, IN (US); and Dalton Snyder, West Lafayette, IN (US)
Assigned to Purdue Research Foundation, West Lafayette, IN (US)
Filed by Purdue Research Foundation, West Lafayette, IN (US)
Filed on Jun. 6, 2022, as Appl. No. 17/833,337.
Application 17/833,337 is a continuation of application No. 16/073,993, granted, now 11,355,328, issued on Jun. 7, 2022, previously published as PCT/US2017/027415, filed on Apr. 13, 2017.
Claims priority of provisional application 62/321,915, filed on Apr. 13, 2016.
Prior Publication US 2022/0392756 A1, Dec. 8, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. H01J 49/00 (2006.01); H01J 49/42 (2006.01)
CPC H01J 49/0031 (2013.01) [H01J 49/42 (2013.01); H01J 49/426 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A system, the system comprising:
a mass spectrometer comprising an ion trap; and
a central processing unit (CPU), and storage coupled to the CPU for storing instructions that when executed by the CPU cause the system to apply a dual frequency waveform to the ion trap that ejects non-target ions from the ion trap while retaining a target ion in the ion trap, wherein the dual frequency waveform consists of a combination of two linear resonances, wherein a first of the two linear resonances is chosen to eject the non-target ions lower in mass than the target ion and a second of the two linear resonances is chosen to eject the non-target ions higher in mass than the target ion, wherein the two linear resonances are applied over a plurality of time points.