| CPC G01N 29/222 (2013.01) [G01N 29/022 (2013.01); G01N 29/2437 (2013.01); H03H 9/175 (2013.01); G01N 2291/0255 (2013.01); G01N 2291/0426 (2013.01)] | 20 Claims |

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1. A sensor with a droplet retaining structure comprising:
a substrate defining a target surface and a retaining structure extending at least partially around the target surface,
wherein the retaining structure comprises a channel having a height extending in a direction orthogonal to the target surface and into the substrate, and a width extending in a direction parallel to the target surface; and
a resonating structure disposed on the target surface of the substrate,
wherein a portion of the target surface between the resonating structure and the retaining structure has a width that allows for full coverage of the resonating structure with a droplet of functionalized material such that the droplet of functionalized material auto-aligns with the resonating structure and is prevented from moving.
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