US 12,332,210 B2
Techniques for sample analysis using product ion collision-cross section information
Russell Julian Mortishire-Smith, Macclesfield (GB); Hans Vissers, Breda (NL); and Michael McCullagh, Northwich (GB)
Assigned to Waters Technologies Ireland Limited, Dublin (IE)
Appl. No. 17/795,658
Filed by Waters Technologies Ireland Limited, Dublin (IE)
PCT Filed Jan. 29, 2021, PCT No. PCT/IB2021/050733
§ 371(c)(1), (2) Date Jul. 27, 2022,
PCT Pub. No. WO2021/152538, PCT Pub. Date Aug. 5, 2021.
Claims priority of application No. 2001249 (GB), filed on Jan. 29, 2020.
Prior Publication US 2023/0084362 A1, Mar. 16, 2023
Int. Cl. G01N 27/622 (2021.01); G16B 40/10 (2019.01); H01J 49/00 (2006.01)
CPC G01N 27/622 (2013.01) [G16B 40/10 (2019.02); H01J 49/0036 (2013.01)] 14 Claims
OG exemplary drawing
 
1. An apparatus, comprising:
at least one memory; and
logic coupled to the at least one memory, the logic to:
receive analytical information for a plurality of product ions, the analytical information comprising product ion collision cross-section (CCS) information,
for at least one product ion of the plurality of product ions, determine a variance value of the product ion CCS information, and
determine that the analytical information comprises information for one or more of a plurality of substructural configurations or a plurality of isomers of the at least one product ion responsive to the variance value being over a variance threshold.